2017~2020年郑州某儿童医院轮状病毒肠炎流行病学特征及影响因素分析

Analysis on epidemiological characteristics and influencing factors of rotavirus enteritis at a children’s hospital, Zhengzhou,2017-2020

目的分析轮状病毒肠炎发病的流行病学特征及影响因素,以期降低小儿轮状病毒肠炎的发生率。方法回顾性分析近年郑州某儿童医院250例轮状病毒肠炎临床资料,并进行单因素和多因素分析。结果轮状病毒肠炎好发于秋冬季(9月至次年的2月)(84.40%)、城镇(60.40%)、≤3岁儿童(94.80%)。经多因素Logistic回归分析,看护人对疾病认知度不足(OR=1.63,95%CI:1.14~2.32)、患儿有高危接触史是(OR=1.88,95%CI:1.15~3.07)引起轮状病毒肠炎的独立危险因素。餐前洗手(OR=0.58,95%CI:0.38~0.94)、儿童粪便及时清理(OR=0.47,95%CI:0.31~0.72)、有轮状病毒疫苗接种史(OR=0.58,95%CI:0.40~0.84)是轮状病毒肠炎感染的保护性因素(OR<1,P<0.05)。结论轮状病毒肠炎好发于秋冬季、城镇和3岁及以下儿童。

Objective To analyze the epidemiological characteristics and influencing factors of rotavirus enteritis, so as to reduce the incidence of rotavirus enteritis in children. Methods The clinical data of 250 cases of rotavirus enteritis in a children in children’s hospital Zhengzhou in recent years were retrospectively analyzed, and univariate and multivariate analysis were performed. Results Rotavirus enteritis in children usually occurred in autumn and winter(September-February of the following year)(84.40%),urban areas(60.40%),and children ≤3 years old(94.80%).After multivariate logistic regression analysis, the lack of knowledge of caregivers(OR=1.63,95%CI:1.14-2.32)and the history of high-risk exposure in children(OR=1.88,95%CI:1.15-3.07) were independent risk factors for rotavirus enteritis in children.Washing hands before meals(OR=0.58,95%CI:0.38-0.94),timely cleaning of children’s feces(OR=0.47,95%CI:0.31-0.72),and a history of rotavirus vaccination(OR=0.58,95%CI:0.40-0.84)were protective factors for rotavirus enteritis infection in children(OR<1,P<0.05). Conclusion Rotavirus enteritis is common in autumn and winter, urban areas and children ≤3 years old.