摘要
目的探讨2019版亚洲肌少症诊断共识对肌少症早期诊断的影响,并筛查肌少症相关危险因素,以促进早期干预。方法2019年6—9月,以方便抽样法选取西安市2所养老院202例老人为研究对象,采用新旧诊断共识对比分析肌少症患病率,不同年龄段、不同体重指数(body mass index,BMI)段与肌少症检出率相关性分析。基于2019版亚洲肌少症诊断共识从基本情况、基础疾病和营养膳食等角度综合分析肌少症相关危险因素,探讨其与肌少症患病及恶化的关系。结果新旧诊断共识标准下,肌少症患病率分别为30.69%和22.28%。同时,基于新共识的80岁及以上老年人肌少症检出率显著高于旧共识(P=0.042)。非肌少症与肌少症前期Logistic多因素分析结果显示,肌力、静息6 m步速、运动障碍评分差异有统计学意义(P<0.01)。肌少症前期、肌少症(普通型)、严重肌少症年龄、身高、体重、肌含量、静息6 m步速、BMI、合并基础疾病(高血压/糖尿病/高血脂)的差异均有统计学意义(P<0.05)。结论年龄与BMI是影响肌少症检出的因素。肌力、静息6 m步速为其独立诊断因素,运动障碍为其独立影响因素。80岁及以上和/或患有高血压、糖尿病、高血脂三种基础疾病的老年人,应重点关注是否合并肌少症的发生。
Objective To explore the impact of Asian Working Group for Sarcopenia(AWGS)2019 Consensus diagnosis on the early diagnosis of sarcopenia,and to screen the risk factors related to sarcopenia,so as to promote early intervention.Methods From June to September 2019,the convenient sampling method was adopted to select 202 elderly persons from 2 nursing homes in Xi′an as the research subjects.The prevalence of sarcopenia was compared with the old and new consensus on diagnosis.Correlation of different age,body mass index(BMI)with detection rate of sarcopenia was analyzed.Based on AWGS 2019 consensus,the risk factors related to sarcopenia were comprehensively analyzed from the perspectives of basic condition,underlying diseases and nutritional diet,and their relationship with the development and progression of sarcopenia was discussed.Results The prevalence of sarcopenia under the new and old consensus on diagnostic criteria was 30.69%and 22.28%respectively.Meanwhile,the sarcopenia detection rate under the new consensus was significantly higher than that of the old consensus(P=0.042).The results of Logistic multivariate analysis showed that muscle strength,6-meter walking speed under resting state and movement disorder score were statistically different between non-sarcosis and sarcosis(P<0.01).Among the groups of pre-sarcopenia,sarcopenia(common type)and severe sarcopenia,significant differences were detected in age,height,weight,muscle mass,6-meter walking speed under resting state,BMI,and underlying diseases(i.e.hypertension,diabetes and hyperlipemia)(P<0.05).Conclusion Age and BMI was influencing factors for the detection of sarcopenia.Muscle strength and 6-meter walking speed under resting state are the independent diagnostic factors,and movement disorder is the independent influencing factor.The elderly persons(age≥80)and/or accompanying with hypertension,diabetes and hyperlipidemia are the high-risk population forsarcopenia.
作者
程蕊
王晶
张克英
宋显东
万毅
秦绪军
CHEN Rui;WANG Jing;ZHANG Ke-ying;SONG Xian-dong;WAN Yi;QIN Xu-jun(Department of Urology, the First Affiliated Hospital of Air Force Medical University of Chinese People′s Liberation Army, Shaanxi Province, Xi′an 710032, China;Department of Health Services, Health Logistics Training Base, Air Force Medical University of Chinese People′s Liberation Army, Shaanxi Province, Xi′an 710032, China;Department of Military Health Education and Management, Air Force Medical University of Chinese People′s Liberation Army, Shaanxi Province, Xi′an 710032, China)
出处
《河北医科大学学报》
CAS
2021年第12期1421-1425,共5页
Journal of Hebei Medical University
基金
空军军医大学第一附属医院学科助推计划立项资助项目(XJZT18ML30)。
关键词
肌减少症
亚洲肌少症工作组
诊断共识
sarcopenia
Asian Working Group of Sarcopenia
diagnostic consensus