处方前置审核对酮咯酸氨丁三醇临床应用合理性的影响

Influence of pre-prescription review based on drug use evaluation criteria on the rationality of clinical application of Ketorolac Tromethamine

目的探讨处方前置审核自定义设置审查规则对酮咯酸氨丁三醇临床应用合理性的影响。方法根据建立的酮咯酸氨丁三醇药物利用评价(DUE)标准自定义设置处方前置审核规则,并运用于临床科室。采用回顾性研究,随机抽取亳州市人民医院开展处方前置审核前后使用酮咯酸氨丁三醇的各130例患者归档病历,基于属性层次模型(AHM)法对其合理性进行评价。结果处方前置审核前病历平均得分为(75.70±14.28)分,审核后病历平均得分为(87.48±11.45)分,差异具有统计学意义(P<0.05);审核前酮咯酸氨丁三醇人均费用为(250±414)元;审核后人均费用为(128±148)元,差异具有统计学意义(P<0.05)。审核后适应证、疗程、联合用药及疗效指标的合理数均有明显提升,增长率均超过15%。结论基于DUE标准自定义设置处方前置审核规则可以促进酮咯酸氨丁三醇的合理使用,降低酮咯酸氨丁三醇的人均费用。

Objective This study was designed to explore the influence of custom rules of pre-prescription review on the rationality of clinical application of Ketorolac Tromethamine. Methods According to the established drug use evaluation(DUE)criteria of Ketorolac Tromethamine,the prescription pre-review rules were customized and applied to clinical departments. A retrospective study was conducted based on the established drug use evaluation criteria of Ketorolac Tromethamine,and analytic hierarchical model(AHM)method was used to evaluate the rationality of each 130 cases of Ketorolac Tromethamine before and after pre-prescription review in People’s Hospital of Bozhou and 260 cases were randomly selected. Results The average medical record score before the pre-prescription review was 75. 70±14. 28,the average medical record score after the pre-prescription review was 87. 48±11. 45,it was statistically significant(P<0. 05). The per capita cost of Ketorolac Tromethamine was(250±414)yuan before the pre-prescription review,and the per capita cost of Ketorolac Tromethamine after the pre-prescription review was(128±148)yuan,and it was statistically significant(P<0. 05). The reasonable rate of indications,course of treatment,combination medication and curative effect had been improved after the pre-prescription review,the growth rate is more than 15%. Conclusion The customized rules of pre-prescription review based on drug use evaluation criteria can promote the rational use of Ketorolac Tromethamine and reduce the per capita cost of Ketorolac Tromethamine.