鼓室内注射地塞米松联合褪黑素治疗单侧急性耳鸣的疗效及可行性分析

Efficacy and feasibility analysis of intramuscular injection of dexamethasone combined with melatonin in the treatment of unilateral acute tinnitus

目的分析鼓室内注射地塞米松联合褪黑素治疗单侧急性耳鸣的疗效及可行性。方法选取我院单侧急性耳鸣患者88例(2019年4月~2020年8月),随机分为褪黑素治疗的对照组(44例)与联合鼓室内注射地塞米松治疗的观察组(44例),观察患者耳鸣情况及不良反应发生率。结果与对照组相比,观察组耳鸣响度评分低,耳鸣意识低,P<0.05;两组不良反应发生率对比,P>0.05。结论给予单侧急性耳鸣患者鼓室内注射地塞米松联合褪黑素治疗,能促进患者耳鸣症状的改善,且不良反应少,值得借鉴。

Objective To analyze the efficacy and feasibility of intramural injection of dexamethasone combined with melatonin in the treatment of unilateral acute tinnitus.Methods A total of 88 patients with unilateral acute tinnitus (April 2019 to August 2020) in our hospital were selected and randomly divided into control group (44 cases) treated with melatonin and observation group (44 cases) treated with combined injection of dexamethasone in the tympanum.The tinnitus situation and the incidence of adverse reactions of the patients were observed.Results Compared with the control group,the tinnitus loudness score and tinnitus awareness in the observation group were lower (P < 0.05).The incidence of adverse reactions was compared between the two groups,P > 0.05.Conclusion Intra-tympanic injection of dexamethasone combined with melatonin in patients with unilateral acute tinnitus can promote the improvement of tinnitus symptoms,with less adverse reactions,which is worthy of reference.