合并HIV感染的肛周脓肿术后使用抗生素与否的临床效果观察

Clinical effect on whether to use antibiotics after operation of perianal abscess complicated with human immunodeficiency virus infection

目的探讨合并HIV感染的肛周脓肿患者脓肿切开引流术后使用抗生素与否的临床效果。方法回顾性分析我院2019年1月至2021年1月收治的47例合并HIV感染的肛周脓肿患者的临床资料,根据脓肿切开引流术后是否使用抗生素将患者分为未使用抗生素组(n=22)和使用抗生素组(n=25)。比较两组术后切口大小、切口愈合时间、脓肿复发及肛瘘形成情况。结果两组术后切口大小、切口愈合时间、脓肿复发率及肛瘘形成率比较差异均无统计学意义(均P>0.05)。结论合并HIV感染的肛周脓肿患者术后使用抗生素与否对临床效果影响不明显。

Objectives To investigate the effect of antibiotics therapy for perianal abscess in patients with human immunodefi⁃ciency virus(HIV)infection who underwent surgical drainage.Methods This was a retrospective analysis of 47 perianal abscess patients with HIV infection treated at our hospital between January 2019 and January 2021.Depending on whether antibiotics were prescribed after surgical drainage,patients were divided into no-antibiotics group(n=22)and antibiotics group(n=25).Size of the incision,time to incision healing,recurrence,and new fistula formation were compared between the two groups.Results The two groups did not differ significantly in the incision size,time to incision healing,recurrence of abscess,and new fistula formation(P>0.05).Conclusion Antibiotics therapy was not effective for perianal abscess in patients with HIV infection who un⁃derwent surgical drainage.