百合地黄汤加味联合普鲁卡因治疗肺结核咯血的临床效果研究

Clinical effect of Baihe Dihuang Decoction combined with procaine on hemoptysis due to pulmonary tuberculosis

目的 探讨在肺结核咯血患者治疗中以普鲁卡因与百合地黄汤实施联合治疗的有效性。方法 86例肺结核咯血患者,以治疗方案不同分为常规组和实验组,每组43例。两组患者均给予常规治疗,常规组在此基础上给予普鲁卡因治疗,实验组在常规组基础上给予百合地黄汤治疗。比较两组患者近期疗效、用药治疗期间不良反应发生情况、疾病复发情况、咯血停止时间、住院时间及治疗后生活质量评分。结果 实验组患者近期总有效率为95.3%,高于常规组的81.4%,差异具有统计学意义(P<0.05)。实验组患者治疗期间不良反应发生率4.7%、疾病复发率7.0%均低于常规组20.9%、25.6%,差异具有统计学意义(P<0.05)。实验组患者咯血停止时间为(4.1±0.4)d、住院时间为(9.0±1.2)d,均短于常规组的(5.2±0.5)、(12.7±2.1)d,差异具有统计学意义(P<0.05)。治疗后,实验组患者物质生活状态、社会功能、躯体功能及心理功能评分均高于常规组,差异具有统计学意义(P<0.05)。结论 相较于单一应用普鲁卡因,联合百合地黄汤对肺结核咯血患者展开治疗,不仅能够缩短患者住院时间,降低疾病复发率,还能改善其预后质量,建议临床推广应用。

Objective To discuss the effectiveness of Baihe Dihuang Decoction combined with procaine on hemoptysis due to pulmonary tuberculosis.Methods A total of 86 patients with hemoptysis due to pulmonary tuberculosis were divided into conventional group and experimental group according to different treatment schemes,with 43 cases in each group.Both groups received conventional treatment.On this basis,the conventional group was treated with procaine,and the experimental group was treated with Baihe Dihuang Decoction on the basis of the conventional group.Both groups were compared in terms of short-term efficacy,occurrence of adverse reactions during treatment,recurrence of the disease,hemoptysis stopping time,hospitalization time and the quality of life score after treatment.Results The total short-term effective rate in the experimental group was 95.3%,which was higher than 81.4%in the conventional group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions during treatment 4.7%and recurrence rate of the disease 7.0%in the experimental group was lower than 20.9%and 25.6%in the conventional group,and the difference was statistically significant(P<0.05).The hemoptysis stopping time(4.1±0.4)d and hospitalization time(9.0±1.2)d of the experimental group were shorter than(5.2±0.5)and(12.7±2.1)d of the conventional group,and the difference was statistically significant(P<0.05).After treatment,the scores of material life,social function,physical function and psychological function of the experimental group were higher than those of the conventional group,and the difference was statistically significant(P<0.05).Conclusion Compared with procaine alone,the combination of Baihe Dihuang Decoction can not only shorten the hospitalization time,reduce the recurrence of the disease,but also improve the prognosis of patients,which is recommended to be popularized and applied.