基于王氏养生三法的中医体质调节在非酒精性脂肪性肝病患者中的应用分析

Analysis of TCM constitution regulation based on three methods of wang’s health preservation in patients with nonalcoholic fatty liver disease

目的对比分析在非酒精性脂肪性肝病(NAFLD)患者中应用基于王氏养生三法进行中医体质调节的临床效果。方法选择2020年1月—12月于医院接受治疗的100例NAFLD患者为研究对象,将其按照随机数字表法区分为对照组、普通减重组、养生1组、养生2组和养生3组(每组各20例),对照组未进行养生,亦不参加有氧运动;普通减重组每日坚持中等量有氧运动30 min,每周5次,或每天高强度有氧运动2 min,每周3次,同时做8~10组阻抗训练,每周2次;干预1组每周养生2次;干预2组每周养生2~5次;干预3组每周养生>5次;5组患者观测时间为24周,8周检测1次,评估5组患者干预中中医体质、BMI、WHR、FBG、TG、TC、LSM、CAP变化情况。结果评估显示干预前、干预8周、干预16周和干预24周过程中,对照组、普通减重组、干预1组的中医体质无明显变化(P>0.05);干预2组和干预3组在干预8周、干预16周以及干预24周时同干预前比较,平和质变化明显(P<0.05),干预2组和干预3组平和质占比在干预过程中无明显变化(P>0.05);干预前5组患者BMI、WHR、FBG、TG、TC、LSM及CAP组间差异无统计学意义,干预后干预2组和3组显著优于其他组别(均P<0.05)。结论在NAFLD患者中开展基于王氏养生三法的中医体质调节可明显提高其平和质者比例,改善肝脏LSM、CAP水平和相关代谢指标。

Objective To compare and analyze the clinical effect of TCM constitution regulation based on Wang’s three methods of health preservation in patients with nonalcoholic fatty liver disease(NAFLD). Methods 100 patients with NAFLD who received treatment in our hospital from January 2020 to December 2020 were selected as the study subjects and divided into three groups according to the random number: control group, common reduction group, health preservation group 1, and health preservation group 2(20 patients in each group). The control group did not undergo health preservation and did not participate in aerobic exercise. The common reduction group adhered to moderate aerobic exercise for 30 minutes a week, 5 times a week, or high intensity aerobic exercise for 2 minutes a day, 3 times a week. At the same time, 8-10 groups of impedance training were done, 2 times a week, intervention group 1 health preservation twice a week, intervention group 2 health preservation 2-5 times a week, intervention group 3 health preservation over 5 times a week. The changes of TCM constitution, BMI, WHR, FBG, TG, TC, LSM and CAP in the five groups were evaluated. Results The evaluation showed that before intervention, 8 weeks of intervention, 16 weeks of intervention, and 24 weeks of intervention, there was no significant change in the TCM constitution of the control group, ordinary reduction and reorganization, and intervention group 1(P>0.05). The intervention group 2 and the intervention group 3 were in the intervention At 8 weeks, 16 weeks of intervention, and 24 weeks of intervention, the peace quality changed significantly(P<0.05), and the proportion of peace quality in the intervention group 2 and intervention group 3 did not change significantly during the intervention(P>0.05);Before the intervention, there was no significant difference in BMI, WHR, FBG, TG, TC, LSM and CAP among the 5 groups of patients. After the intervention, the intervention group 2 and 3 were significantly better than the other groups(all P<0.05). Conclusion Carrying out TCM constitution regulation based on Wang’s three methods of health preservation in NAFLD patients can significantly improve their peaceful quality ratio and improve liver LSM, CAP levels and related metabolic parameters.