急性脑梗死患者发生脑微出血的影响因素分析

Analysis of influencing factors of cerebral microbleed in patients with acute cerebral infarction

目的:分析急性脑梗死(ACI)患者发生脑微出血(CMBs)的影响因素。方法:回顾性分析2017年1月至2020年12月该院收治的70例ACI患者的临床资料。统计ACI患者入院3 d内CMBs发生率,并采用单因素及多因素Logistic分析ACI并发CMBs的危险因素。结果:70例ACI患者发生CMBs 28例,发生率为40.00%;合并高血压、糖尿病,血清低密度脂蛋白胆固醇(LDL-C)>3.37 mmol/L、血清胱抑素C(Cys-C)>1.09 mg/L是ACI患者并发CMBs的独立危险因素(OR>1,P<0.05)。结论:ACI患者并发CMBs的风险较高,其中合并高血压、糖尿病,血清LDL-C>3.37 mmol/L、Cys-C>1.09 mg/L是ACI患者并发CMBs的独立危险因素,临床上应重视对上述因素的早期评估,并采取有效措施干预。

Objective:To analyzed influencing factors of cerebral microbleeds(CMBs)in patients with acute cerebral infarction(ACI).Methods:A retrospective analysis of the clinical data of 70 ACI patients admitted to our hospital from January 2017 to December 2020 was performed.The incidence of CMBs in the ACI patients within 3 days of admission was statistically analyzed.Univariate analysis and multivariate analysis were used to find out the risk factors of ACI complicated by CMBs.Results:Among the 70 ACI patients,28 cases of CMBs occurred with an incidence rate of 40.00%.Combined hypertension and diabetes,serum low-density lipoprotein cholesterol(LDL-C)>3.37 mmol/L and serum cystatin C(Cys-C)>1.09 mg/L were the independent risk factors for ACI complicated by CMBs(OR>1,P<0.05).Conclusions:ACI patients have a higher risk of CMBs.Among them,hypertension and diabetes,serum LDL-C>3.37 mmol/L and Cys-C>1.09 mg/L are independent risk factors for ACI patients with CMBs,and the above factors should be paid attention to clinically.Early assessment of the situation,and effective measures to intervene.