双水平气道正压通气模式在重症肺炎合并呼吸衰竭患者机械通气治疗中的效果

Effects of bi-level positive airway pressure mechanical ventilation on patients with severe pneumonia and respiratory failure

目的:观察双水平气道正压通气(BiPAP)模式在重症肺炎合并呼吸衰竭患者机械通气治疗中的效果。方法:选取90例重症肺炎合并呼吸衰竭患者为研究对象,按随机数字表法分为对照组和观察组各45例。对照组采用持续气道正压通气(CPAP)模式,观察组采用BiPAP模式。比较两组治疗前后心率(HR)、动脉血氧分压(PaO_(2))、动脉血二氧化碳分压(PaCO_(2))、动脉血氧饱和度(SaO_(2))和呼吸频率(RR),以及转气管插管率。结果:治疗后,观察组PaO_(2)和SaO_(2)水平均高于对照组,HR、PaCO_(2)和RR水平均低于对照组,差异有统计学意义(P<0.05);观察组气管插管率为44.44%(20/45),低于对照组的73.33%(33/45),差异有统计学意义(P<0.05)。结论:BiPAP模式用于重症肺炎合并呼吸衰竭患者机械通气治疗中可提高PaO_(2)和SaO_(2)水平,降低HR、PaCO_(2)、RR水平和气管插管率,效果优于CPAP模式。

Objective:To observe effects of bi-level positive airway pressure(BiPAP)mechanical ventilation on patients with severe pneumonia and respiratory failure.Methods:90 patients with severe pneumonia and respiratory failure were selected as the research objects,and were divided into control group and observation group according to the random number table method,45 cases in each.The control group was given continuous positive airway pressure(CPAP)mode,while the observation group was given BiPAP mode.The levels of heart rate(HR),arterial partial pressure of oxygen(PaO_(2)),arterial partial pressure of carbon dioxide(PaCO_(2)),arterial oxygen saturation(SaO_(2)),respiratory rate(RR),and the tracheal intubation rate were compared between the two groups before and after the treatment.Results:After treatment,the PaO_(2) and SaO_(2) levels of the observation group were higher than those of the control group;the HR,PaCO_(2) and RR levels were lower than those of the control group;and the differences were statistically significant(P<0.05).Further,the tracheal intubation rate in the observation group was 44.44%(20/45),which was lower than 73.33%(33/45)in the control group,and the difference was statistically significant(P<0.05).Conclusions:BiPAP mode mechanical ventilation for the patients with severe pneumonia and respiratory failure can increase the PaO_(2) and SaO_(2) levels,reduce the HR,PaCO_(2),RR levels and the tracheal intubation rate.Moreover,it is superior to CPAP mode.