三甲复脉汤加减治疗更年期综合征患者的效果

Effects of Sanjia Fumai decoction on climacteric syndrome

目的:观察三甲复脉汤加减治疗更年期综合征(CS)患者的效果。方法:选取84例CS患者作为研究对象,按照随机数字表法分为对照组和研究组各42例。对照组给予西医常规治疗,研究组在对照组的基础上联合三甲复脉汤加减治疗,比较两组治疗前后中医证候积分、性激素水平[黄体生成素(LH)、促卵泡激素(FSH)、雌二醇(E_(2))]及不良反应发生率。结果:治疗后,研究组中医证候积分低于对照组,差异有统计学意义(P<0.05);研究组LH、FSH水平低于对照组,E_(2)水平高于对照组,差异均有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:三甲复脉汤加减联合西医常规治疗应用于CS患者,可降低中医证候积分,改善性激素水平,且安全性较高,其效果优于单纯西医常规治疗。

Objective:To observe effects of Sanjia Fumai decoction on climacteric syndrome(CS).Methods:84 CS patients were selected as the research objects,and were divided into control group and study group according to the random number table method,each with 42 cases.The control group was given conventional western medicine treatment,while the study group was combined with Sanjia Fumai decoction on the basis of that of the control group.The scores of TCM syndromes,the sex hormone levels[luteinizing hormone(LH),follicle stimulating hormone(FSH),estradiol(E_(2))]and the incidence of adverse reactions were compared between the two groups before and after the treatment.Results:After the treatment,the scores of TCM syndromes in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).The LH and FSH levels of the study group were lower than those of the control group;the E_(2) level was higher than that of the control group;and the differences were statistically significant(P<0.05).However,there was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Sanjia Fumai decoction combined with conventional western medicine in the treatment of the patients with CS can reduce the TCM syndrome score,improve the levels of sex hormones,and has high safety.Moreover,it is superior to single conventional western medicine treatment.