病原微生物检验在治疗细菌性腹泻患儿中的应用价值

Application value of pathogenic microorganism test in treatment of children with bacterial diarrhea

目的:探讨病原微生物检验在治疗细菌性腹泻患儿中的应用价值。方法:选取150例细菌性腹泻患儿为研究对象,采集其粪便标本,采用病原微生物检验法测定其微生物分布情况并进行药敏试验,探讨病原微生物检验在治疗细菌性腹泻患儿中的应用价值。结果:细菌性腹泻患儿病原微生物占比:志贺菌属51.41%、沙门菌属23.94%、致泻性大肠埃希菌14.79%、弧菌属7.04%、嗜水气单胞菌1.41%、铜绿假单胞菌0.70%、金黄色葡萄球菌0.70%;城镇、农村患儿主要病原菌占比分布率比较,差异无统计学意义(P>0.05);沙门菌属1~3岁患儿占比高于>3岁患儿,志贺菌>3岁患儿占比高于1~3岁患儿,差异均有统计学意义(P<0.05)。各细菌对头孢哌酮、头孢三嗪、阿莫西林、头孢噻肟、环丙沙星等药物有不同程度的耐药性。其中,除沙门菌外,各细菌属对头孢哌酮的耐药性均≥50.00%。结论:细菌性腹泻患儿的致病微生物种类繁多,采用病原微生物检验,可为合理选择抗生素提供参考。

Objective:To explore application value of pathogenic microorganism test in treatment of children with bacterial diarrhea.Methods:150 children with bacterial diarrhea were selected as the research objects.The fecal specimens were selected,and the pathogenic microorganism test method was used to determine the microbial distribution status.The drug sensitivity test was performed.The application value of pathogenic microbial test in the treatment of children with bacterial diarrhea was explored.Results:Proportion of pathogenic microorganisms in children with bacterial diarrhea:Shigella species 51.41%,Salmonella 23.94%,diarrheal Escherichia coli 14.79%,Vibrio 7.04%,Aeromonas hydrophila 1.41%,Pseudomonas aeruginosa 0.70%,Staphylococcus aureus 0.70%.There was no statistically significant difference in the distribution rate of the main pathogenic bacteria among the children in urban and rural areas(P>0.05).The proportion of the children with Salmonella 1-3 years old was higher than that of the children>3 years old;the proportion of Shigella>3 years old children was higher than the children 1-3 years old;and the differences were statistically significant(P<0.05).All bacteria had varying degrees of resistance to Cefoperazone,Cefoperazone,Amoxicillin,Cefotaxime,Ciprofloxacin and other drugs.Among them,except Salmonella,all bacteria were resistant to Cefoperazone with the resistance rate≥50.00%.Conclusions:There are many types of pathogenic microorganisms in the children with bacterial diarrhea.The use of pathogenic microorganism testing can provide a reference for the rational selection of antibiotics.