妊娠晚期孕妇B族链球菌感染对母婴结局的影响

Effects of Group B Streptococcus infection on maternal-infant outcomes of pregnant women

目的:观察妊娠晚期孕妇B族链球菌(GBS)感染对母婴结局的影响。方法:选取268名晚期孕妇为研究对象,均进行细菌培养,观察晚期孕妇GBS带菌率,并按是否感染GBS,分为GBS阳性组和GBS阴性组,比较两组不良妊娠结局和新生儿不良结局发生率。结果:268名孕妇中,29例为GBS阳性,GBS带菌率为10.82%(29/268);GBS阳性组胎膜早破(PROM)、胎儿窘迫(FD)、宫内感染(IAI)发生率均明显高于GBS阴性组,差异有统计学意义(P<0.05);GBS阳性组新生儿不良结局发生率为34.48%,明显高于GBS阴性组的12.97%,差异有统计学意义(P<0.05)。结论:妊娠晚期孕妇GBS感染可增加PROM、FD、IAI和新生儿不良结局发生率。

Objective:To observe effects of Group B Streptococcus(GNS)infection on maternal-infant outcomes of pregnant women.Methods:268 late pregnant women were selected as the research subjects,and they were all tested for bacterial culture.The GBS carrying rate was observed.According to whether they were infected with GBS,they were divided into GBS positive group and GBS negative group.The incidence of adverse pregnancy outcomes and the incidence of adverse neonatal outcomes were compared between the two groups.Results:Among the 268 pregnant women,29 cases were GBS positive,and the GBS carrying rate was 10.82%(29/268).The incidences of premature rupture of membranes(PROM),fetal distress(FD),and intrauterine infection(IAI)in the GBS positive group were significantly higher than those in the GBS negative group,and the differences were statistically significant(P<0.05).The incidence of adverse neonatal outcomes in the GBS positive group was 34.48%,which was significantly higher than the 12.97%in the GBS negative group,and the difference was statistically significant(P<0.05).Conclusions:GBS infection in the late pregnant women can increase the incidence of PROM,FD,IAI and the incidence of adverse neonatal outcomes.