过敏性紫癜患儿复发的危险因素分析

Analysis of risk factors for recurrence in children with Henoch-Schonlein purpura

目的:探讨过敏性紫癜(HSP)患儿复发的危险因素。方法:选取91例HSP患儿作为研究对象,随访1年,根据随访结果分为复发组22例与未复发组69例,收集两组临床资料,采用Logistic回归分析HSP患儿复发的危险因素。结果:两组性别、年龄、家族史、补充免疫球蛋白情况比较,差异均无统计学意义(P>0.05);复发组呼吸道感染、未限制饮食、白细胞升高占比均高于未复发组,差异有统计学意义(P<0.05);Logistic回归分析显示,呼吸道感染、未限制饮食、白细胞升高均为HSP患儿复发的独立危险因素(P<0.05)。结论:呼吸道感染、未限制饮食和白细胞升高均为HSP患儿复发的危险因素。

Objective:To analyze risk factors for recurrence in children with allergic purpura.Methods:91 children with HSP were selected as the research objects and were followed up for 1 year.According to the follow-up results,they were divided into recurrence group(22 cases)and non-recurrence group(69 cases).The clinical data of two groups were collected.Logistic regression was used to analyze the risk factors of recurrence in the children with HSP.Results:There were no significant differences in gender,age,family history,and supplementary immunoglobulin between the two groups(P>0.05).The proportions of respiratory tract infections,unrestricted diet,and elevated white blood cells in the recurrence group were higher than those in the non-recurrence group,and the differences were statistically significant(P<0.05).Logistic regression analysis showed that respiratory tract infections,unrestricted diet,and elevated white blood cells were the independent risk factors for recurrence in the children with HSP(P<0.05).Conclusions:Respiratory tract infections,unrestricted diet,and elevated white blood cells were the independent risk factors for recurrence in the children with HSP.