含催化单元的单层保护纳米Au水解酶的研究进展

Development of monolayer-protected gold clusters-based hydrolytic nanozymes containing catalytic units

纳米酶能够在生理条件下催化天然酶所介导的生化反应,表现出天然酶所具有的反应动力学过程和催化机制.在单层保护纳米Au (Au MPCs)表面自组装催化单元可大大提高纳米酶的催化能力,近年来发展迅速.本文总结了近年来含催化单元的Au MPCs水解酶的研究进展,重点讨论了Au MPCs水解酶表层催化单元的设计、超分子组装及其应用.

Nanozymes can catalyze the biochemical reactions mediated by natural enzymes under physiological conditions, and show natural enzymes-like reaction kinetics and catalytic mechanism. Monolayer-protected gold clusters(Au MPCs) containing catalytic units can greatly improve the catalytic abilitys of nanozymes, so it has been developed rapidly in recent years. In this review, the progress of Au MPCs hydrolytic nanozymes containing catalytic units in recent years is summarized. The design of surface catalytic units, supramolecular assembly and application of Au MPCs hydrolytic nanozymes are discussed.