慢性阻塞性肺疾病相关肌少症的诊断与治疗

Diagnosis and treatment of chronic obstructive pulmonary disease-related sarcopenia

慢性阻塞性肺疾病是常见的慢性呼吸系统疾病之一。肌少症是一种以骨骼肌质量下降和功能减退为特点的退行性病变。慢性阻塞性肺疾病病人更易罹患肌少症,同时肌肉质量和功能与肺功能及预后显著相关。本文结合最新文献就慢性阻塞性肺疾病相关肌少症的流行病学、危险因素、发病机制、筛查诊断及药物治疗、营养支持、运动及康复治疗等干预措施予以综述。

Chronic obstructive pulmonary disease is one of the common chronic respiratory diseases. Sarcopenia is a degenerative disease characterized by decreased skeletal muscle mass and decreased function. Patients with chronic obstructive pulmonary disease are more likely to develop sarcopenia, and muscle mass and function are significantly associated with lung function and prognosis. This article reviewed the latest literature to discuss the epidemiology, risk factors, pathogenesis, screening diagnosis and intervention measures including drug treatment, nutritional support,exercise and rehabilitation of chronic obstructive pulmonary disease-related sarcopenia.