摘要
全球约有1/4的人感染结核分枝杆菌,其中大约有5%~10%的感染者会发展成为结核病患者。在校学生人员密集,学校出现肺结核患者很容易造成聚集性发病。对学生进行结核分枝杆菌潜伏感染主动筛查,提前采取预防性治疗等干预措施,对减少结核病后续发病和传播具有重要意义。作者总结了学校结核分枝杆菌潜伏感染的流行现状,对不同筛查方法进行分析,并对学生潜伏感染预防性治疗的对象、方案、效果、不良反应及可行性等问题进行梳理,为学校结核病防控工作提供参考和借鉴。
About a quarter of the whole population were infected with Mycobacterium tuberculosis worldwide,of which about 5%-10%will develop into tuberculosis patients.Students with pulmonary tuberculosis in the schools,were prone to cause cluster diseases.Implementing active screening,preventive treatment and other intervention measures in advance were significantly to reduce the secondary cases and the spread of tuberculosis in schools.This article summarized the epidemic status of latent tuberculosis infection of the students in schools,analyzed the testing results of different screening methods,and summarized the objective,treatment scheme,treatment outcome,side effect and feasibility of preventive treatment for students with latent tuberculosis infection,aiming to provide policy suggestion for the prevention and control of the latent infection of students in schools.
作者
杨奎
陈伟
YANG Kui;CHEN Wei(National Center for Tuberculosis Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China)
出处
《结核与肺部疾病杂志》
2021年第4期361-365,共5页
Journal of Tuberculosis and Lung Disease
基金
国家自然科学基金面上项目(12071268)。
