老年人肝硬化食管胃静脉曲张的临床研究

Clinical study of the elderly cirrhosis gastroesophageal varices

目的分析肝硬化食管胃静脉曲张老年患者的临床特点。方法回顾性分析2017年1月至2020年1月中国人民解放军总医院第一医学中心消化内科医学部诊疗的168例65岁以上肝硬化食管胃静脉曲张老年患者的一般资料、临床表现、内镜下表现及治疗情况等。结果纳入研究的168名老年患者的平均年龄为70.8岁,其中男性74例,占44.0%;女性94例,占56.0%。全部老年患者病因的前3位是乙肝肝硬化(26.8%),酒精性肝硬化(14.9%)和原发性胆汁性肝硬化(12.5%)。老年患者合并各类基础疾病较多,如合并各类心血管系统疾病(44.0%),合并各类内分泌系统疾病(36.9%)。大多数老年患者仅能耐受1-3次内镜下治疗(72.4%)。结论老年人肝硬化食管胃静脉曲张患者的病因复杂,合并基础病较多,治疗相对困难。

Objective To analyze the clinical features of patients with cirrhosis gastroesophageal varices.Methods Retrospective analysis from January 2017 to January 2020,168 cases with cirrhosis gastroesophageal varices of Senior Department of Gsatroenterology,the First Medical Center of PLA General Hospital,who not younger than 65 years old,clinical manifestations,endoscopic performance and treatment,etc.Results The average age of 168 elderly patients was 70.8 years old,including 74 males(44.0%),94 women(56.0%).The top three of the causes of all elderly patients were hepatitis B cirrhosis(26.8%),alcoholic cirrhosis(14.9%)and primary biliary cirrhosis(12.5%).Elderly patients combined with more basic diseases,such as cardiovascular diseases(44.0%),and endocrine system diseases(36.9%).Most older patients can only tolerate 1-3 endoscopic treatment(72.4%).Conclusion The etiology of elderly cirrhosis patients with gastroesophageal varices is complex,complicated with more basic diseases,and their treatment is relatively difficult.