六字诀对脑卒中后认知障碍患者认知功能及血脂水平的影响

Effects of Six-character formula on cognitive function and lipid level of patients with post stroke cognitive impairment

目的探讨六字诀治疗脑卒中后认知障碍(post stroke cognitive impairment,PSCI)患者认知功能的效果及其对血脂水平的影响。方法选取2020年5月至11月于福建中医药大学附属康复医院进行治疗的34例PSCI患者,采用计算机随机分组,对照组及六字诀组各17例,对照组进行常规治疗、康复训练与护理,六字诀组在对照组基础上增加健身气功·六字诀训练,训练6~8 min/遍,3遍/次,1次/d,7 d/周,共进行12周训练。于干预前后采用福州版蒙特利尔认知评估量表(Chinese Fuzhou version of Montreal Cognitive Assessment Scale,MoCA-ChiFZ)评估患者的认知功能并抽血检测血脂水平。使用IBM SPSS 25.0对数据进行统计分析。结果干预前两组患者一般资料及指标差异无统计学意义,具有可比性。干预后,六字诀组MoCA-ChiFZ总分(23.56±1.71)分及注意维度评分5(5~6)分较对照组(22.31±1.66)分、4.5(4~5)分明显增高,差异具有统计学意义(P<0.05),其余维度评分差异无统计学意义(P>0.05);六字诀组三酰甘油(1.42±0.49)mmol/L水平明显低于对照组(2.13±0.86)mmol/L,差异具有统计学意义(P<0.05),其余血脂指标差异无统计学意义(P>0.05)。结论12周的健身气功·六字诀可有效改善PSCI患者的认知功能和三酰甘油水平,对PSCI患者具有良好的康复效果。

Objective To investigate the effect of Six-character formula on cognitive function and lipid level of patients with post stroke cognitive impairment(PSCI).Methods A total of 34 patients with PSCI who were treated in the Rehabilitation Hospital Affiliated to Fujian University of Traditional Chinese Medicine from May to November 2020 were selected randomly divided into control group(n=17)and Six-character formula group(n=17).The control group received routine treatment,rehabilitation training and nursing.On the basis of the control group,fitness Qigong and Six-character formula training was added to the Six-character formula group,training for 6~8 min/time,3 times/time,1 time/day,7 days/week,for 12 weeks in total.Before and after the intervention,the cognitive function of the patients was assessed with the Chinese Fuzhou Version of Montreal Cognitive Assessment Scale(MoCA-CHiFZ)and blood samples were taken to detect blood lipid levels.IBM SPSS 25.0 was used for statistical analysis of the data.Results Before intervention,there was no significant difference in general data and indicators between the two groups,indicating comparability.After intervention,the total score of MoCA-CHiFZ(23.56±1.71)and the score of attention dimension5(5~6)in the Six-character formula group were significantly higher than those in the control group(22.31±1.66)and 4.5(4~5),and the difference was statistically significant(P<0.05),but there was no significant difference in other dimensions(P>0.05).The level of triacylglycerol(1.42±0.49)mmol/L in the Six-character formula group was significantly lower than that in the control group(2.13±0.86)mmol/L,and the difference was statistically significant(P<0.05),while there was no significant difference in other lipid indexes(P>0.05).Conclusion Twelve weeks of fitness Qigong and Six-character formula can effectively improve the cognitive function and triglyceride level of PSCI patients,and has a good rehabilitation effect on PSCI patients.