新疆农村地区成人脂质蓄积指数与糖尿病患病风险的关系

Correlation Analysis of Lipid Accumulation Product and Diabetes in Adults From Xinjiang Rural Areas

目的在新疆农村地区探讨脂质蓄积指数(lipid accumulation product,LAP)与糖尿病患病的关系。方法选择2017年10月—2018年10月在新疆吉木萨尔县泉子街镇卫生院常规体检的成年人共4215例,计算LAP并分析其与糖尿病、体质量指数、腰围、血压和血脂的关系。结果根据LAP四分位数和性别进行分组。随着LAP水平升高,全部研究对象的年龄、体质量指数、腰围、血压和血糖均呈现出逐渐升高的趋势,男性的吸烟、饮酒和有糖尿病家族史的比例亦逐渐升高。无论是男性还是女性,较高LAP水平各组的糖尿病患病风险均明显高于低LAP水平组。结论新疆农村地区体检人群LAP水平升高可能是糖尿病的独立危险因素。

Objective To investigate the relationship between lipid accumulation product(LAP)and diabetes.Methods A cross-sectional study with 4215 subjects taking health examination in Quanzijie health clinic from October 2017 to October 2018 was conducted.LAP was calculated and its relationship with diabetes,body mass index,waist circumference,blood pressure and lipids profiles was explored respectively.Results Subjects were divided into different groups according to LAP quartiles and sex.In all subjects,LAP increased with age,BMI,WC,BP and glucose levels.In addition,higher LAP was associated with smoking,alcoholic drinking and family diabetes history in males.Diabetes risks in higher LAP groups were significantly higher than those in lower LAP groups both in females and males.Conclusion Elevated LAP may be an independent risk factor for diabetes in subjects taking health examination from Xinjiang rural areas.