阿司匹林联合硫酸氢氯吡格雷治疗脑梗死患者的临床效果

Clinical Effect of Aspirin Combined With Clopidogrel on Patients With Cerebral Infarction

目的探讨阿司匹林与硫酸氢氯吡格雷联合治疗脑梗死患者临床疗效及对神经功能缺损评分影响。方法选取2019年1月—2020年1月于我院神经内科收治的脑梗死患者60例,将其平均分为观察组和对照组。对照组选择阿司匹林作治疗药物,观察组在对照组治疗基础上联合硫酸氢氯吡格雷为治疗方案,比较两组患者的临床疗效及神经功能缺损改善情况。结果观察组治疗有效率高于对照组对应值(90.00%>66.67%);观察组不良反应发生率低于对照组对应值(16.67%<40.00%);观察组神经功能缺损评分低于对照组对应值;观察组生活能力评分高于对照组对应值,差异有统计学意义(P<0.05)。结论针对脑梗死患者选择阿司匹林联合硫酸氢氯吡格雷进行治疗,能有效提高患者治疗有效率和改善其神经功能缺损情况,且药物不良反应少,患者日常生活能力水平高,整体效果显著,值得推广。

Objective To study the clinical effect of aspirin combined with clopidogrel on cerebral infarction patients and its influence on the score of neurological impairment.Methods Sixty patients with cerebral infarction admitted to the Department of Neurology from January 2019 to January 2020 were randomly selected and divided into observation group and control group.The control group was treated with aspirin,and the observation group was treated with clopidogrel bisulfate on the basis of the control group.Results The treatment efficiency in the observation group was higher than that in the control group(90.00%>66.67%),the incidence of adverse reactions in the observation group was lower than that in the control group(16.67%<40.00%),and the score of neurological impairment in the observation group was lower than that in the control group.The score of living ability in the observation group was higher than that in the control group(P<0.05).Conclusion The combination of aspirin and clopidogrel sulfate can effectively improve the efficiency of treatment and improve the condition of neurological deficit in patients with cerebral infarction,with fewer adverse drug reactions and high level of daily living ability,the overall effect is remarkable,is worth the clinical vigorously promotion.