慢性阻塞性肺疾病急性加重期患者DVT形成的危险因素分析及干预措施

Analysis of risk factors and intervention measures of deep vein thrombosis in patients with acute exacerbation of chronic obstructive pulmonary disease in emergency ICU

目的探讨急诊重症监护室(EICU)慢性阻塞性肺痰病急性加重期(AECOPD)患者深静脉血栓(DVT)形成的危险因素及其干预措施。方法回顾性分析2018年2月-2020年11月就诊于本院EICU的235例AECOPD患者临床资料,分析AECOPD患者DVT形成的危险因素。结果235例AECOPD患者中发生DVT 30例(12.77%);单因素分析结果显示,年龄、卧床时间、D-D水平与AECOPD患者DVT形成有关(P<0.05);多因素Logistic分析结果显示,年龄≥60岁、卧床时间≥3d、D-D>2mg/L是AECOPD患者DVT形成的危险因素(P<0.05)。结论AECOPD患者DVT形成与年龄、卧床时间、D-D水平密切相关,实施针对性干预措施可降低DVT发生率。

Objective To explore the risk factors and intervention measures of deep vein thrombosis(DVT)in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD)in emergency intensive care unit(EICU).Methods The clinical data of 235 AECOPD patients who were admitted to the emergency ICU ward of our hospital from February 2018 to November 2020 were retrospectively analyzed,and the risk factors of DVT in emergency AECOPD patients were analyzed.Results 30 of the 235 AECOPD patients developed DVT(12.77%);univariate analysis showed that age,bed time,and D-D level were related to the formation of DVT in AECOPD patients,and the difference was statistically significant(P<0.05);Multivariate analysis showed that age≥60 years,bed time≥3d,DD>2mg/L are high risk factors for DVT formation in AECOPD patients(P<0.05).Conclusion The formation of DVT in EICU patients with AECOPD is closely related to age,time in bed,and D-D level.The implementation of targeted interventions is expected to reduce the incidence of DVT.