青光眼睫状体炎综合征患者焦虑抑郁状态调查及其相关因素分析

Survey on anxiety,depression status and the related factors in patients with Posner-Schlossman syndrome

目的探讨青光眼睫状体炎综合征(PSS)患者焦虑、抑郁状态,并对可能的影响因素进行相关分析。方法选取2019年5月至2021年7月温州医科大学附属眼视光医院杭州院区收治的PSS患者180例,收集患者的社会人口学资料及临床资料,采用综合性医院焦虑和抑郁量表(HADS)评估患者的焦虑和抑郁程度,采用中文版青光眼患者生活质量15项量表(CHI-GQL15)评估患者生活质量。采用Spearman秩相关分析PSS患者焦虑、抑郁评分与社会人口学特征、临床特征及生活质量的相关性,并通过多元线性回归分析进行验证。结果180例PSS患者中,有19例(10.56%)为焦虑阳性,有13例(7.22%)为抑郁阳性,其中有7例(3.89%)焦虑、抑郁均为阳性。Spearman秩相关分析及多元线性回归分析均显示,PSS患者焦虑、抑郁评分与平均年收入均呈负相关(均P<0.05),与平均每年复发次数均呈正相关(均P<0.05)。焦虑评分与文化程度无相关性(P>0.05),而抑郁评分与文化程度呈正相关(P<0.05)。结论PSS患者中存在焦虑、抑郁的心理状态,且低收入、高学历和复发次数多的PSS患者更容易出现焦虑或抑郁心理,临床上应多关注此类人群的心理状态。

Objective To survey the anxiety and depression status in patients with Posner-Schlossman syndrome(PSS)and analyze the relevant factors.Methods A total of 180 patients with PSS admitted from May 2019 to July 2021 were enrolled in the study.The hospital anxiety and depression scale(HADS)was used to evaluate psychological distresses.The Chinese version of glaucoma quality of life-15 questionnaire(CHI-GQL15)was used to evaluate the quality of life.The sociodemographic and clinical data of the patients were collected.Spearman correlation analysis and multiple linear regression were used to explore the factors related to anxiety and depression in patients with PSS.Results Of 180 PSS patients,19(10.56%)were positive for anxiety,13(7.22%)were positive for depression,7(3.89%)were positive for both anxiety and depression.Spearman correlation analysis and multiple linear regression analysis showed that the anxiety and depression scores of PSS patients were negatively correlated with the average annual income and positively correlated with the frequency of recurrence(all P<0.05).The depression score was positively correlated with educational level(P<0.05),but anxiety score was not correlated with educational level(P>0.05).Conclusion The status of anxiety and depression exists in patients with PSS,particularly in those with lower annual income,high educational level or frequent recurrence.