动脉型肺动脉高压的危险分层评估工具及其临床应用

Risk Stratification Assessment Tools for Pulmonary Arterial Hypertension and Its Clinical Application

动脉型肺动脉高压是一类慢性疾病,需长期靶向药物治疗,持续的随访评估对病情变化及靶向药物治疗效果评价尤为重要。目前,国内外指南都推荐将肺动脉高压危险分层工具作为指导药物选择、评价药物治疗反应以及指导治疗方案调整的重要手段。目前肺动脉高压的危险分层工具较多,各有优劣。现对常见的肺动脉高压危险分层评估方法以及其临床应用做一综述。

Pulmonary arterial hypertension(PAH)is a chronic disease,which requires long-term targeted therapy.Continuous follow-up assessment is critically important to evaluate the progression of disease and the response of targeted treatment.Both domestic and foreign guidelines recommend the PAH risk stratification tools as important evidences of guiding drug selection,evaluating drug response and guiding therapy regimen adjustment.At present,there are many risk stratification tools for PAH,each with its own advantages and disadvantages.This article reviews the common methods of PAH risk stratification tools and their clinical applications.