中西医结合疗法对小儿支气管哮喘肺功能的影响

Influence of Integrated Traditional Chinese and Western Medicine on Lung Function of Children with Bronchial Asthma

目的:分析清热化痰、平喘宣肺方联合常规西医治疗对小儿支气管哮喘肺通气功能以及免疫功能的影响。方法:随机选取新乡医学院第一附属医院于2017年12月至2018年12月期间收治的92例小儿支气管哮喘,采用双盲法将所有患儿平均分为观察组(46例,采用清热化痰、平喘宣肺方剂联合常规西医治疗)与对照组(46例,采用常规西医治疗)。分别比较两组患儿的免疫功能以及肺通气功能情况。结果:治疗前两组患儿的1 s用力呼气容积(FEV1)、最大呼气流量(PEF)比较,差异无统计学意义(P>0.05);治疗后观察组患儿的FEV1、PEF均较对照组高,差异具有统计学意义(P<0.05)。治疗前两组患儿的免疫球蛋白E(IgE)、CD4^(+)、CD8^(+)比较,差异无统计学意义(P>0.05);治疗后观察组患儿的IgE、CD4^(+)、CD8^(+)均较对照组低,差异具有统计学意义(P<0.05)。结论:通过给予小儿支气管哮喘实施清热化痰、平喘宣肺方剂联合常规西药治疗,可有效改善患儿免疫功能,并提升其肺通气功能。

Objective To analyze the effect of Qingre Huatan and Pingchuan Xuanfei prescription combined with conventional western medicine on pulmonary ventilation function and immune function of children with bronchial asthma.Methods 92 cases of children with bronchial asthma were randomly selected from the first affiliated hospital of Xinxiang medical college from December 2017 to December 2018.With average by double-blind method,all children were divided into observation group(46 cases,using Qingre Huatan and Pingchuan Xuanfei prescription combined with conventional Western medicine)and control group(46 cases,using conventional western medicine therapy).The immune function and lung ventilation function were compared between the two groups.Results There were no significant differences in forced expiratory volume(FEV1)and maximum expiratory flow(PEF)between the two groups before treatment(P>0.05).After treatment,FEV1 and PEF in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).There were no significant differences in immunoglobulin E(IgE),CD4^(+)and CD8^(+)between the two groups before treatment(P>0.05).After treatment,the IgE,CD4^(+)and CD8^(+)levels in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusion The treatment of Qingre Huatan and Pingchuan Xuanfei prescription combined with conventional Western medicine for children with bronchial asthma,can effectively improve the immune function of children and enhance their lung ventilation function,which is a treatment with high practical application value.