补肾健脾方联合艾灸治疗波塞冬组4卵巢低预后不孕症效果

Study of Bushen Jianpi Recipe Combined with Moxibustion in the Treatment of POSEIDON Criteria Group 4 of Low-prognosis Infertility Patients

目的:探讨中药补肾健脾方联合艾灸神阙、足三里对波塞冬组4卵巢低预后不孕症患者卵巢功能的改善作用。方法:选取湖北省妇幼保健院2019年8月至2020年8月期间收治的30例波塞冬组4卵巢低预后不孕症患者,患者均采用中药补肾健脾自拟方口服联合艾灸神阙、足三里治疗,疗程3个月,观察治疗前后患者中医证候积分、抗苗勒管激素(AMH)、血清卵泡刺激素(FSH)、窦卵泡计数(AFC)、卵巢体积(OV)的差异。结果:与治疗前相比,治疗后患者中医证候积分、性激素水平、AFC、OV较治疗前均有明显改善,差异具有统计学意义(P<0.05)。结论:中药补肾健脾自拟方联合艾灸神阙、足三里治疗可显著改善波塞冬组4卵巢低预后不孕症患者的临床症状和卵巢功能。

Objective To investigate the effect of Bushen Jianpi Recipe combined with moxibustion at Shenque and Zusanli on ovarian function of infertile patients with low prognosis in POSEIDON criteria group 4.Methods 30 patients who met the inclusion criteria were treated with Bushen Jianpi self-made recipe combined with moxibustion at Shenque and Zusanli for 3 months.The differences of TCM syndrome score,anti-Mullerian hormone(AMH),follicle-stimulating hormone(FSH),antral follicle count(AFC)and ovarian volume(OV)were observed before and after treatment.Results Compared with before treatment,TCM syndrome score,sex hormone level,antral follicle count and ovarian volume were significantly improved after treatment(P<0.05).Conclusion Bushen Jianpi self-made recipe combined with moxibustion at Shenque and Zusanli can significantly improve the clinical symptoms and ovarian function of infertile patients with low prognosis in POSEIDON criteria group 4.