POCT血糖仪与全自动生化分析仪血糖检测结果比较

Comparison and Analysis of Blood Glucose Test Results Between POCT Blood Glucose Meter and Automatic Biochemical Analyzer

目的:比较血糖检测中即时检验(POCT)血糖仪与全自动生化分析仪的临床应用效果。方法:选取江门市新会区人民医院2018年3月至2020年3月期间收治的100例糖尿病患者及健康体检者,获得不同葡萄糖浓度的静脉全血样本,4例≤2.8 mmol·L^(-1)纳入1组;16例介于2.8~<4.2 mmol·L^(-1)纳入2组;20例介于4.2~<6.7 mmol·L^(-1)纳入3组;30例介于6.7~<11.1 mmol·L^(-1)纳入4组;14例介于11.1~<16.6 mmol·L^(-1)纳入5组;8例介于16.6~22.2 mmol·L^(-1)纳入6组;8例>22.2 mmol·L^(-1)纳入7组。通过42台POCT血糖仪与全自动生化分析仪对各组血糖进行检测,比较分析两种仪器的检测效果。结果:经检测结果显示,各组POCT血糖仪检测结果与全自动生化分析仪检测结果比较,差异均无统计学意义(P>0.05)。线性回归分析显示,4组和5组相关系数r值最高,r值0.997~0.999,线性回归方程y=1.0075x+0.1752。所有检测结果均与《便携式葡萄糖仪血液葡萄糖测定指南》中相关判定标准相符合,比对全自动生化分析仪,42台POCT血糖仪的检测结果均在允许范围之内,即参与比对的POCT血糖仪均合格。结论:在血糖检测中,POCT血糖仪与全自动化生化分析仪检结果无显著差异,而且POCT血糖仪操作简单,具备良好的稳定性以及重复性。

Objective To compare the clinical effect of point–of–care testing(POCT)and automatic biochemical analyzer in blood glucose detection.Methods A total of 100 diabetic patients and healthy subjects admitted to Jiangmen Xinhui District People's Hospital from March 2018 to March 2020 were selected.Venous whole blood samples with different glucose concentrations were obtained,and 4 patients≤2.8 mmol·L^(-1) were included in group 1.Sixteen patients with the range of 2.8~<4.2 mmol·L^(-1) were included in group 2.Twenty patients with the range of 4.2~<6.7 mmol·L^(-1) were included in group 3.Thirty patients ranging from 6.7 to 11.1 mmol·L^(-1) were included in group 4.14 ranged from 11.1 to 16.6 mmol·L^(-1) and were included in group 5;Eight patients with the range of 16.6~22.2 mmol·L^(-1) were included in group 6.Eight patients>22.2 mmol·L^(-1) were included in group 7.42 POCT glucose meters and automatic biochemical analyzer were used to detect blood glucose in each group,and the detection effects of the two instruments were compared and analyzed.Results The test results showed that there was no significant difference between the test results of POCT and automatic biochemical analyzer in each group(P>0.05).The linear regression analysis showed that the correlation coefficient r value of group 4 and group 5 was the highest,r value was 0.999~0.997,and the linear regression equation was y=1.0075x+0.1752.All the test results were consistent with the relevant criteria in“The Guideline for Blood Glucose Measurement by Portable Glucose Meter”.The results of the automatic biochemical analyzer and 42 POCT glucose meters were all within the permitted range,that is,all the glucose meters involved in the comparison were qualified.Conclusion In blood glucose detection,POCT blood glucose meter has no significant difference with fully automated biochemical analyzer.POCT blood glucose meter has simple operation,good stability and repeatability.