氨溴索联合CPAP呼吸机治疗新生儿呼吸窘迫综合征临床观察

Clinical Study of Ambroxol Combined with CPAP Ventilator in the Treatment of Neonatal Respiratory Distress Syndrome

目的:采用氨溴索联合持续气道正压通气(CPAP)呼吸机治疗新生儿呼吸窘迫综合征患儿后,对其临床应用效果进行探究。方法:选取2020年3月至2021年3月恩平市人民医院收治的50例新生儿呼吸窘迫综合征患儿,按照电脑排列序号,将所有研究对象分为对照组与观察组,各25例。对照组采用常规治疗,观察组采用氨溴索联合CPAP呼吸机治疗。观察两组患儿治疗后的临床效果、临床指标以及治疗前后吸入气中的吸入氧浓度(FiO_(2))等相关情况。结果:对照组患儿临床治疗总有效率(92.00%)明显低于观察组(76.00%),差异具有统计学意义(P<0.05)。观察组患儿的氧疗时间、住院时间均明显短于对照组,差异具有统计学意义(P<0.05)。两组患儿治疗前FiO_(2)无明显差异(P>0.05);治疗后,观察组FiO_(2)明显低于对照组,差异具有统计学意义(P<0.05)。结论:采用氨溴索联合CPAP呼吸机治疗新生儿呼吸窘迫综合征患儿,能有效降低患儿的FiO_(2),缩短氧疗时间、住院时间,提高治疗效果,促进患儿康复。

Objective Ambroxol combined with continuous positive airway pressure(CPAP)ventilator were applied to treat infants with neonatal respiratory distress syndrome,and the clinical application effects was explored.Methods From March 2020 to March 2021,50 children with neonatal respiratory distress syndrome who were admitted to Enping People’s Hospital were selected,and divided into group A(25 cases)and group B according to the computer serial number(25 cases).Group A was treated with conventional treatment,and group B was treated with ambroxol combined with CPAP ventilator.The clinical effects,clinical indicators,and the fraction of oxygen concentration(FiO_(2))in the inhaled air before and after treatment in the two groups of children were observed and compard.Results The total effective rate of clinical treatment of children in group A(92.00%)was significantly lower than that in group B(76.00%),and the difference was statistically significant(P<0.05).The oxygen therapy time and hospital stay time of the children in group B were significantly shorter than those in group A,and the differences were statistically significant(P<0.05).There was no significant difference in FiO_(2) between the two groups before treatment(P>0.05);after treatment,the FiO_(2) in group B was significantly lower than that in group A,and the difference was statistically significant(P<0.05).Conclusion The use of ambroxol combined with CPAP ventilator to treat children with neonatal respiratory distress syndrome has a definite effect.It can effectively reduce FiO_(2),shorten the time of oxygen therapy and hospitalization,improve the treatment effect,and promote the recovery of children.