我国婴儿配方奶粉脂溶性维生素的科学设计范围研究

Studies on the Scientific Design Scope of Fat-Soluble Vitamins in Chinese Infant Formula

为确定我国婴儿配方奶粉脂溶性维生素A、D、E、K的科学设计范围,给配方研发人员提供参考。首先分析11家实验室对同批次产品的检测数值,确定维生素A、D、E、K用于配方设计的检测偏差分别为15%,15%,25%和20%;然后通过分析母乳数据、适宜摄入量和婴儿配方奶粉标准限量,确定维生素A、D、E、K设计的目标值分别为60μg RE/100 kcal,2μg/100 kcal,0.6 mgα-TE/100 kcal,4.2μg/100 kcal。根据已确定的营养素设计目标值,结合货架期衰减率、实验室间检测偏差推算出合理的设计范围,并与可耐受最高摄入量、市售产品的营养素含量分布作比较,同时兼顾现阶段0~6月龄婴儿的营养状况,确定我国婴儿配方奶粉脂溶性维生素A、D、E、K的科学设计范围分别为100~120μg RE/100 kcal,3.3~4μg/100 kcal,1.2~2.5 mgα-TE/100 kcal和9.3~12μg/100 kcal。

For the purpose of studying the scientific design scope of fat-soluble vitamins A,D,E and K in infant formula milk powder for Chinese babies and providing reference for R&D personnel.Firstly,the test values from 11 different laboratories for the same batch of products were analyzed,the test deviations of vitamin A,D,E and K for formula design were determined to be 15%,15%,25%and 20%,respectively.Secondly,nutrient content in breast milk,adequate intakes,and regulation requirements for infant formula milk powder were compared and analyzed,the formula designing target values of vitamin A,D,E,and K were determined to be 60μg RE/100 kcal,2μg/100 kcal,0.6 mgα-TE/100 kcal,and 4.2μg/100 kcal,respectively.Thirdly,reasonable nutrient design ranges were calculated by the determined target values of formula design,nutrient shelf life loss rate and detection deviation among different laboratories,and compared with tolerable upper intake level,the distribution of nutrients content of products that sold in China,meanwhile,the nutritional status of infants aged 0 to 6 months were taken into account.Finally,the scientific design range of fat-soluble vitamins A,D,E and K in Chinese infant formula milk powder was determined to be 100-120μg RE/100 kcal,3.3-4μg/100 kcal,1.2-2.5mgα-TE/100 kcal and 9.3-12μg/100 kcal respectively.