异蛋白复合凝聚研究进展

Research Progress of Heteroprotein Complex Coacervation

异蛋白复合凝聚是两种带相反电荷的蛋白间发生的一种相分离现象,近年来引起研究者的关注。本文介绍异蛋白复合凝聚的定义和特点;归纳总结常见的异蛋白复合凝聚体系及环境因素对复合凝聚过程的影响;以及异蛋白复合凝聚在小分子活性组分荷载、益生菌包埋、蛋白分离纯化、乳液稳定等方面的应用,并展望了异蛋白复合凝聚的未来研究方向。

Heteroprotein complex coacervation is a phase separation phenomenon that occurs between two oppositely charged proteins,and it has attracted increasing attention from food researchers.This review first introduced the definition and characteristics of the heteroprotein complex coacervation.Then,the typical systems of heteroprotein complex coacervation and the influences of the environmental factors on the coacervation process were summarized.Also,the applications of heteroprotein complex coacervation in the delivery of small molecule bioactives,the probiotic encapsulation,the separation and purification of proteins and the stabilization of emulsions were introduced in detail.Finally,the research direction of heteroprotein complex coacervation was prospected.