不同营养支持途径对脓毒症患者的影响综述

Effect of different nutritional support methods on patients with sepsis

脓毒症易引起胃肠道的急性损伤和功能失调,造成患者营养物质来源不足,进而影响患者的营养状态,甚至危及生命健康。临床上,营养支持是脓毒症患者的重要治疗手段,其分为肠内营养(enteral nutrition,EN)支持途径及肠外营养(parenteral nutrition,PN)支持途径。近年来,EN、PN对于脓毒症作用的研究结论与过去似乎大相径庭,本文旨在从各大指南推荐、大量实验基础和临床观察等方面探讨EN、PN在脓毒症中的作用,为脓毒症患者营养支持途径的选择及预后改善提供参考。

Sepsis is easy to cause acute damage and dysfunction of the gastrointestinal tract,resulting in insufficient of nutrients in the patients,thereby affecting the nutritional status of patients,even threatening life.In clinical,nutritional support is an important treatment for patients with sepsis,which is divided into enteral nutritional support(EN) and parenteral nutritional support(PN).In recent years,the research conclusions on the effects of EN and PN on sepsis seem to be quite different from those in the past.The purpose of this article is to explore the role of EN and PN in sepsis from the recommendations of major guidelines,a large number of experimental foundations,clinical observations and so on,so as to provide references for clinicians in choosing suitable nutritional support and improving the prognosis of patients.