经支气管冷冻肺活检诊断弥漫性肺疾病的应用分析

The application analysis of transbronchial cryobiopsy in diagnosis of diffuse lung disease

目的探讨经支气管冷冻肺活检(TBCB)诊断弥漫性肺疾病(DLD)的临床价值。方法回顾性分析34例诊断不明DLD患者经TBCB检查的临床资料,评价TBCB诊断DLD的安全性及有效性。结果结合临床特征及病理结果,最终共27例(79.4%)获得明确病理形态学诊断,4例(11.8%)经进一步多学科讨论确立诊断,3例仍病因不明,诊断阳性率为91.2%(31/34)。并发症发生情况:气胸9例(26.5%),其中轻度6例、中度3例;出血29例(85.3%),均为1级。结论TBCB对DLD病因诊断确诊率高,安全性良好,住院天数短。

Objective To explore the clinical value of transbronchial cryobiopsy(TBCB)in diagnosis of diffuse pulmonary disease(DLD).Methods The clinical data of 34 patients with unknown DLD examined by TBCB were analyzed retrospectively,to evaluate the safety and efficacy of TBCB in diagnosing DLD.Results According to the clinical features and pathological results,27 cases(79.4%)were confirmed pathomorphological diagnosis,4 cases(11.8%)were further confirmed by multidisciplinary discussion,and 3 cases still had unknown etiology.The positive rate of diagnosis was 91.2%(31/34).Complications:pneumothorax in 9 cases(26.5%),mild in 6 cases and moderate in 3 cases,bleeding after biopsy was grade 1 in 29 cases(85.3%).Conclusion The application of TBCB in the etiological diagnosis of DLD has high diagnostic rate,good safety,low average cost and short hospital stay.