摘要
目的探讨颅内间变性孤立性纤维性肿瘤(solitary fibrous tumor,SFT)/血管周细胞瘤(hemangiopericytoma,HPC)的临床病理特征及发生肝转移后的诊断及治疗。方法回顾性收集兰州大学第二医院2003–2019年期间收治且经手术治疗后出现肝脏及其他器官转移的颅内间变性SFT/HPC患者的临床病理资料。结果 3例颅内间变性SFT/HPC患者均接受手术切除且术后辅以常规放疗。初次干预治疗后有2例患者分别于术后10年和7年复发,3例患者分别于初次干预治疗后11、7、6年出现肝脏转移,其中有1例同时伴子宫、肺及椎体转移。结论颅内间变性SFT/HPC具有高复发和极易颅外转移的风险,肝脏是其常见的转移靶器官,初始干预后肝转移具有延迟性,需要长期密切随访。
Objective To investigate the clinicopathologic features of intracranial anaplastic solitary fibrous tumor(SFT)/hemangiopericytoma(HPC) and diagnosis and treatment after liver metastasis. Method The clinicopathologic data of patients with intracranial anaplastic SFT/HPC who had metastasized to the liver and other organs after surgery were collected from 2003 to 2019 in the Second Hospital of Lanzhou University. Results All 3 patients with intracranial anaplastic SFT/HPC underwent surgical resection and supplemented with conventional radiotherapy after operation. After the initial intervention treatment, 2 patients relapsed at 10 years and 7 years after the operation, and 3 patients had liver metastases at 11, 7, and 6 years after the initial intervention treatment. One of them was accompanied by uterus, lung, and vertebral body metastases. Conclusions Intracranial anaplastic SFT/HPC has a high risk of recurrence and extracranial metastasis. Liver is a common target organ for metastasis of anaplastic SFT/HPC, liver metastasis is delayed after initial intervention of intracranial anaplastic SFT/HPC, it requires a long-term close follow-up.
作者
李向阳
李凡
张树泽
邵全年
焦作义
LI Xiangyang;LI Fan;ZHANG Shuze;SHAO Quannian;JIAO Zuoyi(Department of General Surgery,Second Hospital of Lanzhou University,Lanzhou 730030,P.R.China)
出处
《中国普外基础与临床杂志》
CAS
2021年第12期1593-1598,共6页
Chinese Journal of Bases and Clinics In General Surgery
基金
兰州大学第二医院“萃英科技创新”计划(项目编号:2020QN-21)。
关键词
颅内间变性孤立性纤维性肿瘤/血管周细胞瘤
肝转移
诊断
治疗
intracranial anaplastic solitary fibrous tumor/hemangiopericytoma
liver metastasis
diagnosis
treatment