丁苯酞软胶囊联合阿托伐他汀钙片治疗脑梗死患者的效果

Effect of Butylphthalide Soft Capsule Combined with Atorvastatin Calcium Tablet in the Treatment of Cerebral Infarction and the Influence on the Establishment of Collateral Circulation in Patients

目的探究丁苯酞软胶囊联合阿托伐他汀钙片治疗脑梗死患者的效果。方法此次研究选取100例脑梗死患者,根据不同的治疗方式进行分组,对照组采取常规治疗,观察组采取丁苯酞软胶囊联合阿托伐他汀钙片治疗,对比两组的治疗效果。结果观察组治疗后不同时间段的NIHSS评分均低于对照组,差异有统计学意义(P<0.05)。观察组治疗后不同时间段缺血区脑血流量明显增加,且升高幅度高于对照组(P<0.05)。观察组治疗后SOD、GSH-Px高于对照组,NO水平低于对照组,差异有统计学意义(P<0.05)。观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05)。结论采用丁苯酞软胶囊联合阿托伐他汀钙片治疗脑梗死患者可取得显著的效果,与常规治疗相比,联合治疗具有显著的优势。

Objective To explore the efficacy of butylphthalide soft capsule combined with atorvastatin calcium tablets in the treatment of cerebral infarction.Methods In this study,100 patients with cerebral infarction were selected and grouped according to different treatment methods.The control group was treated with conventional treatment,and the observation group was treated with butylphthalide soft capsules combined with atorvastatin calcium tablets.The treatment effects of the two groups were compared.Results The NIHSS scores of the observation group at different time periods after treatment were lower than those of the control group,and the difference was statistically significant(P<0.05).The cerebral blood flow in the ischemic area of the observation group increased significantly at different time periods after treatment,and the increase rate was higher than that of the control group(P<0.05).After treatment,SOD and GSH-Px of the observation group were higher than those of the control group,and the level of NO was lower than that of the control group.The difference was statistically significant(P<0.05).The total effective rate of treatment in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).Conclusion The use of butylphthalide soft capsules combined with atorvastatin calcium tablets to treat patients with cerebral infarction can achieve significant results.Compared with conventional treatments,combined treatment has significant advantages.