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吖啶衍生物合成及其在医药领域的应用进展

Progress in synthesis and application of acridine derivatives in medicine
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摘要 吖啶衍生物是一类结构特殊的含氮芳香族化合物,具有明显的抗肿瘤、消炎、抗菌、抗艾滋病毒及治疗老年痴呆症等药用活性。近年来,关于吖啶衍生物的合成及在医药领域中的应用得到了快速的发展。概述了吖啶衍生物的合成方法及其在医药领域中的应用进展。 Acridine derivatives are a class of nitrogen containing aromatic compounds with special structure and extensive medical use.They have obvious anti-tumor,anti-inflammatory,anti-bacterial,anti-HIV and anti-Alzheimer disease activities.Therefore,in recent years,the synthesis of acridine derivatives and their applications in the field of medicine have been developed rapidly.In this paper,the synthetic methods of acridine derivatives and their applications in the field of medicine were reviewed.
作者 郭佩佩 王伊 刘晨丹 高琴琴 史梦丹 仝红娟 GUO Pei-pei;WANG Yi;LIU Chen-dan;GAO Qin-qin;SHI Meng-dan;TONG Hong-juan(School of Pharmacy,Shaanxi Institute of International Trade Commerce,Xi’an 712046,China;Collaborative Innovation Center of Green Manufacturing Technology for Traditional Chinese Medicine in Shaanxi Province,Xi’an 712046,China)
出处 《精细与专用化学品》 CAS 2021年第12期25-27,共3页 Fine and Specialty Chemicals
基金 2021年陕西省大学生创新创业训练计划项目(S202113123015)。
关键词 吖啶衍生物 合成 应用 进展 acridine derivatives synthesis application progress
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