益肾行气活血法毫针针刺治疗良性前列腺增生症临床疗效观察

Observation on Clinical Effect of Filiform Needling Therapy of Tonifying Kidney,Promoting Qi and Activating Blood in the Treatment of Benign Prostatic Hyperplasia

【目的】探讨益肾行气活血法毫针针刺治疗良性前列腺增生症的临床疗效。【方法】将68例良性前列腺增生症患者随机分为观察组和对照组,每组各34例。2组患者均给予相关的健康教育,对照组给予坦索罗辛缓释胶囊治疗,观察组在对照组的基础上联合益肾行气活血法毫针针刺治疗(取穴:关元、中极、血海、三阴交、太溪、太冲),疗程为4周。观察2组患者治疗前后中医证候评分、国际前列腺症状评分(IPSS)、生活质量(QOL)评分、超声下前列腺体积、膀胱残余尿量等指标的变化情况,并评价2组患者的临床疗效和安全性。【结果】(1)研究过程中,观察组和对照组各有4例患者脱落,最终各有30例患者完成试验。(2)治疗4周后,观察组的总有效率为86.67%(26/30),对照组为66.67%(20/30),组间比较,观察组的疗效明显优于对照组,差异有统计学意义(P<0.05)。(3)治疗后,2组患者的中医证候评分、IPSS评分、QOL评分和膀胱残余尿量均较治疗前明显降低(P<0.05),且观察组的降低作用均明显优于对照组,差异均有统计学意义(P<0.05);而2组患者治疗前后组内和组间的前列腺体积比较,差异均无统计学意义(P>0.05)。(4)2组患者均未发现有肝肾损害、心脑血管指标异常,以及其他不良反应或不良事件发生。【结论】益肾行气活血法毫针针刺治疗良性前列腺增生症具有较好的疗效。

Objective To investigate the clinical effect of filiform needling therapy of tonifying kidney,promoting qi and activating blood in the treatment of benign prostatic hyperplasia(BPH). Methods Sixty-eight patients with BPH were randomly divided into observation group and control group,34 cases in each group. Both groups were given related health education, and in addition, the control group was given Tamsuloxine Sustained-release Capsules, and the observation group was given Tamsuloxine Sustained-release Capsules together with filiform needling therapy of tonifying kidney,promoting qi and activating blood on the points of Guanyuan(CV4),Zhongji(CV3),Xuehai(SP10),Sanyinjiao(SP6),Taixi(KI3)and Taichong(LR3),the course of treatment lasting4 weeks. The changes of traditional Chinese medicine(TCM)syndrome scores, international prostate symptom scores(IPSS),quality of life(QOL)scores,ultrasound prostate volume,bladder residual urine volume and other indicators in the two groups were observed before and after treatment,and the clinical efficacy and safety of the two groups were also evaluated. Results(1)During the trial,4 patients in each group fell off and 30 patients in each group completed the trial eventually.(2)After 4 weeks of treatment,the total effective rate of the observation group was 86.67%(26/30),and that of the control group was 66.67%(20/30). The intergroup comparison showed that the curative effect of the observation group was significantly superior to that in the control group,and the difference was statistically significant(P < 0.05).(3)After treatment,TCM syndrome scores,IPSS,QOL scores and bladder residual urine volume in the two groups were significantly decreased compared with those before treatment(P <0.05),and the effect on lowering the above indexes in the observation group was significantly superior to that in the control group,the difference being statistically significant(P < 0.05). The pre-and post-treatment intragroup comparison of prostate volume as well as the post-treatment intergroup comparison of the volume showed that the differences were statistically significant(P > 0.05).(4)No liver and kidney damage,abnormal cardiovascular and cerebrovascular indicators,or other adverse reactions or adverse events were found in both groups. Conclusion The filiform needling therapy of tonifying kidney,promoting qi and activating blood exerts certain efficacy in the treatment of BPH.