个体化营养干预对妊娠糖尿病患者血糖及炎症反应控制效果的影响

Effect of individualized nutrition intervention on the control of blood glucose and inflammation with gestational diabetes mellitus patients

目的探究个体化营养干预对妊娠糖尿病(GDM)患者血糖及炎症反应控制效果影响。方法选取邢台医学高等专科学校第二附属医院产科2019年1月至12月收治的120例GDM患者作为研究对象,按照随机数字表法将其分成研究组和对照组,每组各60例。对照组采取常规饮食指导,研究组在对照组的基础上采取个体化营养干预,干预至患者出现分娩先兆停止。比较两组干预前后血糖水平[空腹血糖(FBG)、餐后两小时血糖(2hFBG)]、C-反应蛋白(CRP)及干预后生活质量评价量表评分、护理满意度和围生结局。结果干预后,两组FBG、2hFBG、CRP低于干预前,且研究组低于对照组,差异有统计学意义(P<0.05)。研究组围产期并发症总发生率低于对照组,差异有统计学意义(P<0.05)。研究组不良妊娠结局总发生率低于对照组,差异有统计学意义(P<0.05)。研究组生活质量评分中健康感觉、躯体感觉、睡眠状态、生活满足感及认知功能得分高于对照组,差异有统计学意义(P<0.05)。研究组护理满意度高于对照组,差异有统计学意义(P<0.05)。结论个体化营养干预可有效调节GDM患者血糖水平,减轻患者炎症反应,改善母婴围生结局,还可提高患者生活质量及护理满意度,值得临床推广运用。

Objective To explore the effect of individualized nutrition intervention on the control of blood glucose and inflammation in patients with gestational diabetes mellitus(GDM)patients.Methods A total of 120 patients with GDM who were admitted to the Department of Obstetrics,the Second Affiliated Hospital of Xingtai Medical College from January to December 2019 were selected as the research objects,and they were divided into study group and control group according to the random number table method,with 60 cases in each group.The control group took regular dietary guidance,and the study group took individualized nutritional intervention on the basis of the control group.The intervention was performed until the patient had a threatened cessation of childbirth.The blood glucose levels before and after the intervention(fasting blood glucose[FBG],two hours fasting blood glucose[2hFBG]),C-reactive protein(CRP)were compared,while the short form 36-item health survey score,nursing satisfaction,and perinatal outcome after the intervention were evaluated.Results After the intervention,FBG,2hFBG,and CRP of two groups were lower than those before the intervention,while the study group was lower than the control group,and the differences were statistically significant(P<0.05).The total incidence of perinatal complications in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).The total incidence of adverse pregnancy outcomes in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).The scores of health feeling,physical sensation,sleep state,life satisfaction,and cognitive function in the quality of life score of the study group were higher than those of the control group,and the differences were statistically significant(P<0.05).The nursing satisfaction of the study group was higher than that of the control group,and the difference was statistically significant(P<0.05).Conclusion Individualized nutrition intervention can effectively regulate the blood glucose level of patients with GDM,reduce the inflammatory response of the patients,improve the perinatal outcome of mothers and infants,and can also improve the quality of life and nursing satisfaction of patients.It is worthy of clinical application.