摘要
类风湿关节炎是一种以炎症滑膜炎为主的慢性自身免疫性疾病,致残率高,严重影响患者的生存质量。JAK-STAT信号通路对类风湿关节炎关节滑膜细胞因子的产生和激活发挥重要作用。中药治疗类风湿关节炎有着独特优势,本文就近年来中药经JAK-STAT信号通路治疗类风湿关节炎的机制研究进行简要综述,以期为临床研究和实验研究拓展思路。
Rheumatoid arthritis is a chronic autoimmune disease mainly characterized by inflammatory synovitis,with high morbidity,it seriously affects the quality of life of patients.JAK-STAT signaling pathway plays an important role in the production and activation of synovial cytokines in rheumatoid arthritis joints.Traditional Chinese medicine has unique advantages in treating rheumatoid arthritis.In this paper,the mechanism of traditional Chinese medicine in the treatment of rheumatoid arthritis via JAK-STAT signaling pathway in recent years is briefly reviewed,in order to broaden the thinking for clinical and experimental studies.
作者
高飞
包书茵
奥乌力吉
GAO Fei;BAO Shuyin;Ao Wuliji(Graduate School,Heilongjiang University of Chinese Medicine,Heilongjiang Province,Harbin150040,China;Medical College,Inner Mongolia Minzu University,Inner Mongolia Autonomous Region,Tongliao028000,China;College of Mongolian Medicine,Inner Mongolia Minzu University,Inner Mongolia Autonomous Region,Tongliao028000,China)
出处
《中国医药导报》
CAS
2021年第35期42-45,共4页
China Medical Herald
基金
国家自然科学基金青年科学基金项目(82004070)
内蒙古自治区科技计划项目(2020GG0103)
内蒙古自治区科技计划项目(蒙医药重点实验室建设)。
关键词
类风湿关节炎
中药
JAK-STAT信号通路
研究进展
Rheumatoid arthritis
Traditional Chinese medicine
JAK-STAT signaling pathway
Research progress
