Navien导管抽栓术治疗颅内静脉窦血栓形成效果观察

Navien catheter thrombus aspiration therapy for cerebral venous sinus thrombosis:observation of its curative efficacy

目的探讨Navien导管抽栓术治疗颅内静脉窦血栓形成(CVST)的效果。方法回顾性分析河北医科大学第二医院采用Navien导管抽栓术治疗的13例阻塞范围较广泛的CVST患者,并随访6个月,观察治疗效果。结果13例患者中12例治愈,1例死亡。有8例患者术前伴有不同程度意识障碍,至出院时除1例死亡外,7例均意识清楚。12例患者出院时、术后6个月美国国立卫生研究院卒中量表(NIHSS)评分分别为11(1.5,16)分、5(0,2.75)分,与术前14(2.5,18)分相比,差异均有统计学意义(P<0.01);改良Rankin量表(mRS)评分分别为3(0,3.75)分、0(0,1.75)分,与术前5(2,5)分相比,差异均有统计学意义(P<0.01)。结论应用Navien导管抽栓术治疗CVST有效,可改善患者神经功能,提高生活质量。

Objective To investigate the efficacy of Navien catheter thrombus aspiration therapy in treating cerebral venous sinus thrombosis(CVST).Methods The clinical data of 13 patients with wide extensive CVST,who received Navien catheter thrombus aspiration therapy at the Second Hospital of Hebei Medical University of China,were retrospectively analyzed.The patients were followed up for 6 months.The curative effect was evaluated.Results Of the 13 patients,12 were cured and one died.Eight patients had different degrees of conscious disturbance before treatment,at the time of discharge 7 patients were well-aware and one died.In the 12 patients,the National Institutes of Health Stroke Scale(NIHSS)score at the time of discharge and 6 months after treatment were 11(1.5,16)points and 5(0,2.75)points respectively,which were statistically significant different from preoperative 14(2.5,18)points(P<0.01).The modified Rankin Scale(mRS)score at the time of discharge and 6 months after treatment were 3(0,3.75)points and 0(0,1.75)point respectively,which were statistically significant different from preoperative 5(2,5)points(P<0.01).Conclusion For the treatment of CVST,Navien catheter thrombus aspiration therapy is clinically effective.This therapy can improve the neurological function as well as the life quality of patients.