舒芬太尼联合罗哌卡因在硬膜外麻醉无痛分娩中的应用效果

The Effect of Sufentanil Combined with Ropivacaine in Painless Delivery Under Epidural Anesthesia

目的探究舒芬太尼联合罗哌卡因在硬膜外麻醉无痛分娩中的应用效果。方法选取该院2020年1—12月收治的67名分娩产妇为研究对象,将所有产妇随机分为对照组(n=33)与观察组(n=34)。对照组自然分娩,未做无痛处理;观察组给予舒芬太尼联合罗哌卡因麻醉。观察两组疼痛程度、不良反应发生率、乳房胀痛情况、产程及产后出血量、血气指标。结果麻醉后,观察组0级、1级的疼痛人数明显多于对照组,且观察组2级、3级疼痛人数均为0,少于对照组,差异有统计学意义(Z=-6.807,P<0.05);观察组不良反应发生率(5.88%)低于对照组(36.36%),差异有统计学意义(χ^(2)=9.413,P<0.05);观察组乳房无痛与轻度胀痛例数多于对照组,且观察组中度、重度胀痛人数少于对照组,差异有统计学意义(Z=-3.265,P<0.05);两组第二、三产程相比差异无统计学意义(P﹥0.05),观察组第一产程以及产后出血量低于对照组,差异有统计学意义(t=5.482、8.267,P<0.05);产后,观察组酸碱度(pH)较对照组低,且观察组血二氧化碳分压(PaCO_(2))、动脉血氧分压(PaO_(2))显著高于对照组,差异有统计学意义(t=2.707、3.782、10.920,P<0.05)。结论对分娩产妇给予舒芬太尼联合罗哌卡因麻醉,镇痛效果显著,起效快,安全性高,可显著缩短第一产程,减轻乳房胀痛,减少产后出血量,临床应用效果显著。

Objective To investigate the effect of sufentanil combined with ropivacaine in painless delivery under epidural anesthesia.Methods The 67 delivery women admitted to the hospital from January to December 2020 were selected as the research objects,and all the women were randomly divided into a control group(n=33)and an observation group(n=34).The control group gave birth naturally without painless treatment;the observation group was given sufentanil combined with ropivacaine anesthesia.The pain degree,incidence of adverse reactions,breast pain,labor process and postpartum hemorrhage and blood gas index were observed in the two groups.Results After anesthesia,the number of pain cases of grade 0 and 1 in the observation group was significantly more than that in the control group,and the number of pain cases of grade 2 and 3 in the observation group were 0,which was less than that in the control group,and the difference was statistically significant(Z=-6.807,P<0.05).The incidence of adverse reactions in the observation group(5.88%)was lower than that in the control group(36.36%),and the difference was statistically significant(χ^(2)=9.413,P<0.05).The number of breast painless and mild pain in the observation group was more than that in the control group,and the number of moderate and severe pain in the observation group was less than that in the control group,and the difference was statistically significant(Z=-3.265,P<0.05).There was no statistically significant difference in the second and third stages of labor between the two groups(P>0.05).The first stage of labor and postpartum hemorrhage in the observation group were lower than those in the control group,and the difference was statistically significant(t=5.482,8.267,P<0.05).After delivery,the pH of the observation group was lower than that of the control group,and the partial pressure of carbon dioxide(PaCO_(2))and the partial pressure of arterial oxygen(PaO_(2))of the observation group were significantly higher than those of the control group,and the difference was statistically significant(t=2.707,3.782,10.920,P<0.05).Conclusion Sufentanil combined with ropivacaine is anesthetized for parturient women,which has significant analgesic effect,quick onset and high safety.It can significantly shorten the first stage of labor,reduce breast pain,and reduce postpartum hemorrhage.The clinical application effect is significant.