尿微量白蛋白对糖尿病合并高血压病的检测效果

Detection Effect of Urine Microalbumin on Diabetes Mellitus with Hypertension

目的评估糖尿病合并高血压病患者应用尿微量白蛋白检测的效果。方法选择医院在2020年5月—2021年5月期间就诊的65例糖尿病合并高血压病患者作为观察组,选择同时间段65名健康体检者作为对照组,两组均接受尿微量白蛋白检测,分析尿微量白蛋白对糖尿病合并高血压病的检测效果。结果观察组尿微量白蛋白(59.32±15.63)μmol/L、血清胱抑素C(1.51±0.36)mg/L、尿素氮(8.13±2.23)mmol/L、肌酐(86.65±6.21)mg/mmol均高于对照组的(7.12±1.36)μmol/L、(0.75±0.11)mg/L、(4.55±1.32)mmol/L、(70.23±5.56)mg/mmol,差异有统计学意义(t=26.824、16.277、11.138、15.882,P<0.05)。观察组舒张压(95.60±6.79)mmHg和收缩压(148.96±9.58)mmHg均高于对照组(78.63±8.63)mmHg、(121.63±6.36)mmHg,观察组空腹血糖(10.63±2.39)mmol/L、餐后2 h血糖(11.63±2.15)mmol/L和糖化血红蛋白(7.65±0.79)%均高于对照组的(6.05±2.15)mmol/L、(8.23±1.63)mmol/L、(5.11±0.68)%,差异有统计学意义(t=12.459、19.162、11.486、10.160、19.646,P<0.05)。观察组尿微量白蛋白检测阳性率(67.69%)高于对照组(0.00%),差异有统计学意义(χ^(2)=66.512,P<0.05)。结论尿微量白蛋白对糖尿病合并高血压病患者诊断具有重要价值,可以及时发现肾病,值得在临床中予以推广使用。

Objective To evaluate the effect of urine microalbumin detection in patients with diabetes mellitus and hypertension. Methods The 65 patients with diabetes mellitus and hypertension who were treated in the hospital from May2020 to May 2021 were selected as the observation group. The 65 healthy subjects in the same time period were selected as the control group. Both groups received urine microalbumin detection to analyze the detection effect of urine microalbumin on diabetes mellitus and hypertension. Results In the observation group, urine microalbumin(59.32±15.63) μmol/L, serum cystatin C(1.51±0.36) mg/L, urea nitrogen(8.13±2.23) mmol/L, creatinine(86.65±6.21) mg/mmol, Higher than the control group(7.12±1.36) μmol/L,(0.75±0.11) mg/L,(4.55±1.32) mmol/L,(70.23±5.56) mg/mmol,and the difference was statistically significant(t=26.824, 16.277, 11.138, 15.882, P<0.05). The diastolic blood pressure(95.60±6.79) mmHg and the systolic blood pressure(148.96±9.58) mmHg of the observation group were higher than those of the control group(78.63 ±8.63)mmHg and(121.63 ±6.36) mmHg, and the fasting blood glucose of the observation group(10.63 ±2.39) mmol/L, 2 h postprandial blood glucose(11.63±2.15) mmol/L and glycosylated hemoglobin(7.65±0.79)% were higher than the control group(6.05±2.15) mmol/L,(8.23±1.63) mmol/L,(5.11±0.68)%,and the difference was statistically significant(t=12.459,19.162, 11.486, 10.160, 19.646, P <0.05). The positive rate of urine microalbumin detection in the observation group(67.69%) was higher than that of the control group(0.00%),and the difference was statistically significant(χ^(2)=66.512,P <0.05). Conclusion Urinary microalbumin is of great value in the diagnosis of patients with diabetes mellitus and hypertension, nephropathy can be detected in time, and it is worthy of clinical application.