药学干预在药学联合治疗2型糖尿病中的临床应用价值研究

Study on the Clinical Application Value of Pharmaceutical Intervention in the Treatment of Type 2 Diabetes with Pharmacy

目的观察在2型糖尿病药学联合治疗中实施药学干预的价值。方法选取于2019年10月—2020年10月在该院就诊的116例2型糖尿病患者为研究对象,所有患者均实施药学联合治疗,因药物干预方法差异性予以分组,58例予以药学干预患者纳入观察组,58例予以常规药物指导患者纳入对照组,对比和观察干预效果。结果和对照组相比,观察组用药依从性显著提升(72.41%vs 89.66%),差异有统计学意义(P<0.05);和对照组相比,观察组空腹血糖(5.10±0.55)mmol/L、餐后2 h血糖(8.05±0.48)mmol/L、糖化血红蛋白(5.08±0.85)%显著降低,差异有统计学意义(P<0.05);和对照组相比,观察组不良反应总发生率显著降低(22.41%vs 6.90%),差异有统计学意义(P<0.05);和对照组相比,观察组精神功能、社会功能、躯体功能、心理功能生活质量各项评分显著提升,差异有统计学意义(P<0.05);和对照组相比,观察组干预总满意度显著提升(75.86%vs 94.83%),差异有统计学意义(P<0.05)。结论在2型糖尿病药学联合治疗中实施药学干预可达到满意的干预效果,建议推广。

Objective To observe the value of implementing pharmaceutical intervention in the combined treatment of type2 diabetes. Methods Selected 116 patients with type 2 diabetes who were in the hospital from October 2019 to October2020 as the study subjects. All patients were treated with pharmaceutical combination therapy, and were divided into groups due to differences in drug intervention methods. 58 cases received pharmaceutical intervention of patients were included in the observation group. Fifty-eight cases were given conventional medication guidance of patients were included in the control group. Compared and observed the effect of intervention. Results Compared with the control group, the medication compliance of the observation group was significantly improved(72.41% vs 89.66%), the difference was statistically significant(P <0.05). Compared with the control group, the observation group’s fasting blood glucose(5.10 ±0.55) mmol/L, 2 h postprandial blood glucose(8.05±0.48) mmol/L, and glycosylated hemoglobin(5.08±0.85)% were significantly reduced, and the difference was statistically significant(P<0.05). Compared with the control group, the total incidence of adverse reactions in the observation group was significantly reduced(22.41% vs 6.90%), and the difference was statistically significant(P<0.05). Compared with the control group, the observation group’s mental function, social function, physical function, and mental function quality of life scores were significantly improved, and the difference was statistically significant(P<0.05).Compared with the control group, the observation group’s total satisfaction with intervention was significantly improved(75.86% vs 94.83%), and the difference was statistically significant(P<0.05). Conclusion The implementation of pharmaceutical intervention in the pharmaceutical combined treatment of type 2 diabetes can achieve satisfactory intervention effects, and it is recommended to promote it.