Au/SiO_(2)/mSiO_(2)双面神罐状微米颗粒的制备

Fabrication of Au/SiO_(2)/mSiO_(2)Pot-like Janus Particles

双面神罐状颗粒具有独特的限制性空间,是一种用于构筑微纳米马达较为理想的结构;但是目前报道的双面神罐状颗粒不能在其内表面有效修饰各种生化试剂,导致其在微纳米马达领域的应用场景有限。以聚苯乙烯(PS)微球单层结构为模板,结合磁控溅射技术、溶胶凝胶法和化学蚀刻法制备了一种可用于修饰生物化学试剂的Au/SiO_(2)/mSiO_(2)双面神罐状微米颗粒。探究了双面神罐状微米颗粒的形成机理以及Au层厚度对双面神罐状微米颗粒结构和形貌的影响规律。结果表明,相对于生长在SiO_(2)表面的介孔二氧化硅(mSiO_(2))层,在PS表面直接生长的mSiO_(2)层薄且粗糙,导致它们在机械振荡中容易碎裂从而形成双面神罐状微米颗粒。此外,双面神罐状微米颗粒的强度由Au层厚(d)度决定,随d增加而提高。制备的Au/SiO_(2)/mSiO_(2)双面神罐状微米颗粒可以通过金巯键(Au—S)在内表面修饰各种生化试剂,有望拓宽其在微纳米马达领域的应用范围。

The pot-like Janus particle is an ideal structure for constructing micro/nano motors due to its unique restrictive space.However,currently reported Pot-like Janus Particles can not be effectively modified with biochemical reagents,which limits their application in the micro/nano motors field.Au/SiO_(2)/mSiO_(2)pot-like Janus microparticles were first prepared by combining magnetron sputtering system,sol-gel method and chemical-etching method,using polystyrene(PS)microspheres as template.The formation mechanism of the Au/SiO_(2)/mSiO_(2)pot-like Janus microparticles and the effect of the thickness of Au layer on the structure and morphology of the Au/SiO_(2)/mSiO_(2)pot-like Janus microparticles were investigated.The experimental results show that the mesoporous silica(mSiO_(2))layer grew on the PS surface is relatively thin and rough which will be broken in the process of mechanical oscillation,thus leading to the formation of pot-like Janus microparticles.Additionally,the strength of the pot-like Janus particles was determined by the thickness of Au layer,which enhanced with the increase of the thickness of the Au layer.The as-prepared Au/SiO_(2)/mSiO_(2)pot-like Janus microparticles embedded with an inner Au layer can be used to modify with various biochemical reagents through Au-thiol bond,which lays a foundation for their applications in micro/nanomotor and biomedical fields.