摘要
To the Editor:Optic neuritis(ON)usually ends with one episode,but recurs in 3%to 5%of patients.Among recurrent patients,those that emerge negative from multiple sclerosis or neuromyelitis optica(NMO)workup are diagnosed with chronic relapsing inflammatory optic neuropathy(CRION).This disease group,first named by Kidd et al,[1]refers to a clinical situation in which inflammatory optic nerve inflammation on both sides occurs repeatedly and worsens when steroids or immu-nosuppressants are discontinued.Early diagnosis is important in this group because the risk of blindness is significant,and as such,treatment is focused on preserving vision.However,because a significant number of CRION patients suffer from ocular pain,alleviation of pain should not be overlooked.
