肺段切除术和肺楔形切除术治疗直径≤2cm的外周性肺腺癌围手术期效果分析

A retrospective study of segmentectomy and wedge resection in the treatment of peripheral lung cancer with a diameter of ≤2 cm

目的比较肺段切除术和肺楔形切除术在直径≤2 cm且CT显示结节≥50%表现为磨玻璃样的肺腺癌治疗效果。方法 2020年1月~2021年7我院行肺段切除术或肺楔形切除术的肺腺癌病人38例,根据治疗方法分为两组,段切组16例,采用肺段切除术;楔切组22例,采用肺楔形切除术,比较两组手术相关指标。结果两组均无围术期死亡病例。段切组和楔切组手术时间分别为(131.6±40.2)分钟和(20.3±10.2)分钟,术中失血量分别为(67.2±49.1)ml和(9.9±5.1)ml,引流管拔管时间分别为(3.5±1.5)天和(1.5±0.5)天,住院时间分别为(4.5±3.5)天和(2.5±1.5)天,两组比较差异有统计学意义(P<0.05)。楔切组优于段切组。结论对于外周性(肺实质外1/3)且直径≤2 cm的早期肺腺癌,肺楔形切除优于肺段切除。

Objective To compare the therapeutic effects of segmentectomy and lung wedge resection for lung cancer with a diameter ≤ 2 cm and CT shows that ground glass nodules ≥ 50%.Methods From January 2020 to July 2021,38 patients with lung adenocarcinoma who underwent segmental resection or pulmonary wedge resection at Zhongnan Hospital of Wuhan University were enrolled.Among them: 16 cases in the segmental resection group(segmental resection group);22 cases in the wedge resection group(wedge resection group),compared the clinical data of the two groups of patients.Results There was no perioperative death in both groups.Operation time [(131.6±40.2)min vs.(20.3±10.2) min],intraoperative blood loss [(67.2±49.1) ml vs.(9.9±5.1) ml],drainage tube extubation time[(3.5±1.5)d vs.(1.5±0.5)d] and hospitalization time [(4.5±3.5)d vs.(2.5±1.5)d] in the segmental resection group and the wedge resection group were statistically significant(P<0.05).All these aspects, resection the wedge resection group was significantly better than the segment resection group.Conclusion Pulmonary wedge resection is beneficial to the rapid recovery of patients with peripheral(1/3 of outside the lung parenchyma) and pulmonary adenocarcinoma with diameter ≤2 cm.