内镜黏膜下剥离术治疗患者术中并发出血的相关危险因素分析

Analysis on the Related Risk Factors of Intraoperative Bleeding in Patients Treated with Endoscopic Submucosal Dissection

目的探讨内镜黏膜下剥离术(ESD)治疗患者术中并发出血的相关危险因素。方法回顾性分析2018年3月至2020年3月在我院行ESD治疗的87例早期胃癌患者的临床资料,分析术中并发出血的相关危险因素。结果87例ESD治疗患者术中并发出血25例(28.74%)。单因素分析显示,病变最大直径、病变部位、手术时间、合并溃疡与ESD治疗患者术中并发出血有关(P<0.05);多因素分析显示,病变最大直径>5 cm、病变部位(贲门-胃底部)、手术时间>90 min、合并溃疡是ESD治疗患者术中并发出血的危险因素(P<0.05)。结论病变最大直径>5 cm、病变部位(贲门-胃底部)、手术时间>90 min、合并溃疡是ESD治疗患者术中并发出血的危险因素。

Objective To explore the related risk factors of intraoperative bleeding in patients treated with endoscopic submucosal dissection(ESD).Methods The clinical data of 87 patients with early gastric cancer treated with ESD in our hospital from March 2018 to March 2020 were retrospectively analyzed,and the related risk factors of intraoperative bleeding were analyzed.Results 25 cases(28.74%)had intraoperative bleeding in 87 patients with ESD treatment.Univariate analysis showed that the maximum diameter of the lesion,location of the lesion,operation time,and complication of ulcer were related to intraoperative bleeding in patients treated with ESD.Multivariate analysis showed that the maximum diameter of lesion>5 cm,lesion site(cardia-gastric base),operation time>90 min,and complication of ulcer were the risk factors of intraoperative bleeding in patients with ESD treatment(P<0.05).Conclusions The maximum diameter of lesion>5 cm,lesion site(cardia-gastric base),operation time>90 min,and complication of ulcer are the risk factors of intraoperative bleeding in patients with ESD treatment.