限制性液体复苏在创伤失血性休克救治中的临床应用效果

The clinical effect of restrictive fluid resuscitation in the treatment of hemorrhagic traumatic shock

目的研究限制性液体复苏在创伤失血性休克(HTS)救治中的临床效果。方法66例HTS患者为研究对象,依据随机数字表法分为A组和B组,每组33例。A组采用积极液体复苏,B组采用限制性液体复苏。对比两组患者的凝血功能指标[凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、凝血酶时间(TT)]及并发症发生率。结果复苏后,两组患者的PT、APTT、TT均长于本组复苏前,但B组患者的PT(10.48±1.48)s、APTT(32.73±2.45)s、TT(13.92±1.54)s均短于A组的(11.76±1.53)、(36.59±2.58)、(16.28±1.75)s,差异有统计学意义(P<0.05)。B组患者的并发症发生率6.06%低于A组的24.24%,差异有统计学意义(P<0.05)。结论限制性液体复苏用于救治HTS患者可改善凝血功能、减少并发症,值得推崇。

Objective To study the clinical effect of restrictive fluid resuscitation in the treatment of hemorrhagic traumatic shock(HTS).Methods A total of 66 cases of HTS patients as study subjects were divided into group A and group B according to the random numerical table,with 33 cases in each group.Active fluid resuscitation was used in group A,and restrictive fluid resuscitation was used in group B.The coagulation function indexes[prothrombin time(PT),activated partial thromboplastin time(APTT),thrombin time(TT)]and the complications were compared between the two groups.Results After resuscitation,the PT,APTT,and TT of the two groups were longer than those of this group before resuscitation,but the PT(10.48±1.48)s,APTT(32.73±2.45)s,and TT(13.92±1.54)s of group B were shorter than(11.76±1.53),(36.59±2.58),(16.28±1.75)s of group A.All the differences were statistically significant(P<0.05).The complication rate 6.06%of group B was lower than 24.24%of group A,and the difference was statistically significant(P<0.05).Conclusion Restrictive fluid resuscitation can improve the coagulation function and reduce complications of patients with HTS,which is worthy of promotion.