32例垂体囊肿切除术的临床疗效分析

Clinical effect of pituitary cystectomy in thirty-two patients

目的探讨神经内镜下经鼻蝶入路切除垂体囊肿的手术疗效。方法回顾性分析2013年3月至2019年5月在济宁医学院附属医院采用神经内镜经鼻蝶入路手术治疗和病理确诊为垂体囊肿32例患者的临床资料,总结疗效。结果32例患者中病理诊断Rathke囊肿29例,垂体蛛网膜囊肿3例。利用内镜技术可彻底清除囊肿内容物,清晰观察囊肿与鞍隔及蛛网膜下隙的关系。术后随访0.5~1.0年,患者头痛、头晕及视力障碍均得到不同程度的改善。有1例复发,无严重并发症及死亡病例。结论神经内镜下经鼻蝶入路切除术是垂体囊肿安全、有效的治疗方式。

Objective To discuss the surgical efficacy of neuroendoscopic transsphenoidal approach for the removal of pituitary cystic lesion.Methods Clinical data and efficacy of 32 patients with neuroendoscopic transsphenoidal surgery and pathological diagnosis of pituitary cystic lesion in the Affiliated Hospital of Jining Medical University from March 2013 to May 2019 were retrospectively analyzed.Results Of the 32 patients,29 patients were pathologically diagnosed with Rathke cysts and 3 patients with pituitary arachnoid cysts.The content of cyst could be completely removed and the relationship between cyst and sellarseptum and subarachnoid space could be clearly observed by using endoscopy.After followed-up for 0.5-1.0 year,headic,dizziness and visual impairment were improved.One patient relapsed,without serious complications or death.Conclusions Transsphenoidal neuroendoscopic surgery is a safe and effective treatment for pituitary cystic lesion.