智能负压联合自体富血小板凝胶在糖尿病足Wagner 3~4级中的应用效果

Application effect of intelligent negative pressure combined with autologous platelet-rich gel in Wagner 3-4 grade diabetic foot

目的探讨智能负压联合自体富血小板凝胶在糖尿病足Wagner 3~4级中的应用效果。方法选取2020年2月至2021年5月钦州市第一人民医院住院的80例糖尿病足Wagner 3~4级患者作为研究对象,采用随机数字表法将其分为试验组和对照组,每组各40例。对照组患者采用智能创伤负压综合治疗法,试验组患者采用智能创伤负压联合自体富血小板凝胶治疗。比较两组患者的创面愈合时间、换药次数、溃疡面积、血糖水平、治疗效果及治疗满意度。结果试验组患者治疗4周的换药次数少于对照组,溃疡面积小于对照组,愈合时间短于对照组,血糖水平低于对照组,差异有统计学意义(P<0.05)。试验组患者的治疗总有效率高于对照组,差异有统计学意义(P<0.05)。试验组患者治疗4周的治疗总满意度高于对照组,差异有统计学意义(P<0.05)。结论智能负压联合自体富血小板凝胶治疗糖尿病足Wagner 3~4级,能够有效缓解临床症状,缩小溃疡面积,促进创面快速愈合,住院时间短,满意度高,操作简单,费用低,值得推广应用。

Objective To explore the effect of intelligent negative pressure combined with autologous platelet-rich gel on Wagner 3-4 grade diabetic foot.Methods A total of 80 patients with Wagner 3-4 grade diabetic foot hospitalized in Qinzhou First People′s Hospital from February 2020 to May 2021 were divided into experimental group and control group according to random number table method,with 40 cases in each group.Patients in the control group were treated with intelligent trauma negative pressure comprehensive therapy,patients in the experimental group were treated with intelligent trauma negative pressure combined with autologous platelet-rich gel.The wound healing time,dressing change time,ulcer area,blood glucose level,treatment effect and treatment satisfaction were compared between the two groups.Results The time of dressing change,ulcer area in the experimental group were less than those in the control group,healing time was shorter than that in the control group,and blood glucose level was lower than that in the control group after 4 weeks of treatment,the differences were statistically significant(P<0.05).The total effective rate of the experimental group was higher than that of the control group,the difference was statistically significant(P<0.05).The satisfaction of the experimental group after 4 weeks of treatment was higher than that of the control group,the difference was statistically significant(P<0.05).Conclusion Treatment of Wagner 3-4 diabetic foot by intelligent negative pressure combined with autologous platelet-rich gel can effectively relieve clinical symptoms,reduce ulcer area,promote wound healing,shorten hospital stay and improve satisfaction.It has simple operation and low cost,which is worthy of popularization and application.