临床标本中马红球菌的抗生素敏感性与临床疗效相关

Antibiotic sensitivity of Rhodococcus equi in clinical specimens is correlated with efficacy of clinical treatment

目的分离鉴定临床标本中的马红球菌(R.equi),探讨其对抗生素的敏感性与临床疗效的关系。方法对2019年4月至2020年4月临床科室送检的痰、尿、脑脊液、血培养等标本进行培养;从中选取17例经分离鉴定确定携带马红球菌的患者为治疗组(抗生素敏感性联合用药),另选取17例同期分离鉴定确定携带马红球菌的患者为对照组(经验用药治疗),比较两组治疗效果。结果根据抗生素敏感性联合用药进行临床疗效的比较,治疗组疗效高于对照组(P<0.05)。结论合理选用抗生素联合用药,能明显提高临床疗效的治愈率。

Objective To isolate and identify Rhodococcus equi(R.equi)from clinical specimens for potential relationship between antibiotic sensitivity and efficacy of antibiotic chemotherapy.Methods From April 2019 to April 2020,17 cases patients with positive isolation of R.equi were grouped as test one and and 17 cases of patients underwent empirical treatment only were collected as the control group.Results The efficacy of antibiotic chemotherapy with sensitivity test(test group)showed significantly better than that of the control group.Conclusions Rational use of antibiotics chemotherapy supported by sensitivity test can significantly improve the effect of chemotherapy.