摘要
Sister Mary Joseph nodule(SMJn)or umbilical metastasis was first named by Henry Hamilton Bailey in 1949,and port-site metastasis(PSM)is a novel concern.1,2 The nurse Sister Mary Joseph had noticed umbilical nodules prior to surgery in patients with abdominal cancer,and reported this clinical observation to the Mayo Clinic direction.Since then,the ominous SMJn has been scarcely reported in association with tumors of the stomach,pancreas,colon,rectum,ovary,uterus,and cholangiocarcinoma.1,3-12 The estimated incidence of SMJn is 1%-3%in the general population with malignancy and is often related to gastrointestinal(35%-65%)or genitourinary tumors(12%-35%).3,5 Metastatic routes are peritoneal,bloodborne,lymphatic,along an embryonic structure like the round or falciform ligament,and by the laparoscopic direct implantation.5,7,11 SMJn is usually violaceous to the reddish-brown lesion with up to 5 cm(Fig.1),10,11 but it can be mimicked by endometriosis,fibroma,keloid,abscess,cyst,or hernia.
